Jasmin sutkovic Protein domains a nicer way to predict 3D structure of a protein Domains Fold individually Accelerate the process of ID: 1048224
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1. Protein domains5.12.2019Jasmin sutkovic
2. Protein domains...... a nicer way to predict 3D structure of a protein
3. Domains...Fold individuallyAccelerate the process of foldingReduce the large number of possible residue interactions
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11. Let‘s become smart SMART – Simple Modular Architecture Research ToolIt allows us to identify domains and analyze their architectureDomains are stored in the database based on their phyletic distributions, functional class, tertiary structures and functionally important residues
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14. Normal vs genomic modeThe main difference is in the protein database usedNormal mode contains more databases (proteomes)Genomic mode contains only proteomes of sequenced genomesNormal mode has redundancyGenomic mode is more precise/accurate/reliable but has a smaller database
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22. Finding motifs in the sequence
23. Paste the amino acid sequence in the fieldPress Submit
24. The results are viewed like thisWe can find out the most information from the first few rows, where we can see the domains and some disorder as wellLower rows represent some simillar motifs found in different proteins