PPT-Motifs and Domains ,

Chemical Modifications Dr Hilal AY Protein motifs and domains Protein motifs are small regions of protein threedimensional structure or amino acid sequence shared among different proteins . PHAR . 201/Bioinformatics I. Philip E. Bourne. Department of Pharmacology, . UCSD. pbourne@ucsd.edu. Thanks to Stella . Veretnik. . PHAR 201 Lecture 15 2012. Agenda. What is a 3D domain?. Why are domains important?. John . McGuigan. 05/04/2009. Highly Conserved Elements. The most . conserved elements at least 200 . bp. long. Highly Conserved Elements are a much broader . set than UCEs. At least 200 . bp. long. Parallel Structure: . using the . same pattern . of words to show that two or more ideas have . the . same level of importance. .. Do Now:. Create your own examples of PARALLELISM using the examples as your guide!. Vagelis. . Hristidis. Assistant Professor. School of Computing and Information Sciences. Florida International University (FIU), Miami. Need for Information Discovery. Amount of available data increases. SBI3U1. Mrs. franklin. Taxonomy is . . .. DISCOVERING. NAMING. DESCRIBING. CLASSIFYING. ORGANISMS. Used to better understand biodiversity. In order to describe and classify a new species, one must compare them to other organisms. . By Toni Morrison. Written in:.  New York: 1962–1965. First published in 1970. Setting:. Set in 1941 in Lorain, Ohio, Toni Morrison's novel centers on a particularly difficult year in the life of eleven year old Pecola Breedlove.  Pecola comes from a poor and poorly adjusted black family. . Pietro Ferrara. Chair of Programming . Methodology. ETH Zürich. pietro.ferrara@gmail.com. Who I am. Former student @ . Ca. ’ . Foscari. Bachelor: July 2003. Master: February 2005. PhD student @. Ecole. Batlle Masó, Laura. Rosich. . Sangrà. , Elena. Sumarroca. . Bordas. , Marina. Torrecilas. Testa, Tatiana. INDEX. Introduction. Materials and methods. Monomeric. . helicase. : . PcrA. Hexameric. Three Important Devices: Know These. Symbol: An object that represents something more significant that just itself. Motif: A . recurring. element or idea; a phrase; image; repetition of similar symbols; repetition of an issue/attitude. Cell Networks. University of Heidelberg. Interactions . and Modules: the how and why of molecular interactions. Proteins are modular. Since the early 1970s it has been observed that protein structures are divided into discrete elements or domains that appear to fold, function and evolve independently. . Fiction Genre . Evolves over History. 1. Prose . 2. Novel . 3. Romance. Gothic (Terror). *. Horror . (. Slasher. , . Psychological. ,. scifi. , fantasy). Prose vs. Poetry. Define- Non- . rhyme . Poetry . loops (coil). Bovine . carboxypeptidase. A. Figure 6-28. Tertiary . structures . may contain . common patterns, or motifs, of secondary structures (= . supersecondary. structures) . βαβ. β. -hairpins. simon.andrews@babraham.ac.uk. @. simon_andrews. v. 1.0. 1. Rationale. 2. Gene A. Gene B. Gene C. Hit A. Hit B. Hit C. Prom A. Prom B. Prom C. GGATCC. GGATCC. GGATCC. Basic Questions. Does the sequence around my hits look unusual?. Leila . Shokat. How biologically important is the “Evening Element”?. The Evening Element is a motif in the promoter regions of genes that are regulated by CCA1. 8. . base pairs long. JASPAR. http://.