PPT-Exploring gene regulation during cerebellar development

The cerebellum is the region of the brain that coordinates motor control and many human neural disorders impact the cerebellum Several spontaneous mouse mutants with motor defects have been found including. of gene expression. . References:. . Stryer. : “Biochemistry”, 5. th. Ed.. Hames. & Hooper: “Instant Notes in Biochemistry”, 2. nd. Ed.. 1. Basic principles of gene control. What is gene expression?. Eukaryotic Gene Regulation. How are genes turned on & off . in eukaryotes?. How do cells with the same genes differentiate to perform completely different, specialized functions?. Evolution of gene regulation. Gene Expression Group. 7/14/11. 2011 National Academies Northstar Institute for Undergraduate Education in Biology . Outline. Context. Review: Clicker Questions. Cell Differences (Think-Pair-Share). Regulation of Gene Expression (Mini-Lecture). Pre-transcriptional regulation. chromatin compaction . eg. . deacetylation. , . methylation. transcriptional initiation . ie. transcription factors to activate or repress. alternative promoters =. THINK ABOUT IT . How Does A Cell Know?. Which Gene To . Express. &. Which Gene Should Stay . Silent. ?. Prokaryotic Gene Regulation. @. To conserve resources, prokaryotes regulate their activities, producing only those genes necessary for the cell to function.@ . CSCOPE. Unit: 08 Lesson: 01. There are hundreds of different types of cells in your body, and each type has a unique function. We’re going to compare some different types of cells to see how much they have in common. . Draw 8 boxes on your paper. Gene regulation accounts for some of the phenotypic differences between organisms with similar genes.. 2005-2006. Gene regulation in bacteria. Control of gene expression enables individual bacteria to adjust their metabolism to environmental change. Gene Regulation Gene expression can be turned on, turned off, turned up or turned down! For example, as test time approaches, some of you may note that stomach acid production increases dramatically&# REFERENCES 1 Friedman JR and Kaestner KH The Foxa family of transcription factors in development and metabolism 2006 Cell Mol Life Sci 63 2317-2328 2 Oliveri P Walton KD Davidson EH and McClay DR Repr REFERENCES 1 Friedman JR and Kaestner KH The Foxa family of transcription factors in development and metabolism 2006 Cell Mol Life Sci 63 2317-2328 2 Oliveri P Walton KD Davidson EH and McClay DR Repr (Chapter 9). Presented by Dr. Laurie M. Erickson. Chair of the Department of Health Sciences. Blitstein Institute of Hebrew Theological College. Chicago, IL, USA.. Gene Expression can be Regulated.. Gene expression: . Definition:. Anything genetic above and beyond the . sequence. of nucleotides. Importance:. Everything. , especially development and genetic. responses to the environment.. Examples of Epigenesis:. 1) Development: tissue differentiation and timing. 8.2.1SubdivisionTransverse fissures divide the cerebellum into lobes,lobules and folia,whereas paramedian sulci separatethe median vermis from the hemispheres (Fig.8.1).The flocculus and the nodule fo AP Bio – Ch. 16-21. Unit 6 – Overview. Ch. 16 – The Molecular Basis of Inheritance (DNA). Ch. 17 – Gene Expression: From Gene to Protein. Ch. 18 – Regulation of Gene Expression. Ch. . 19 . – .