PPT-Leuke mia Leukemia is uncontrolled monoclonal proliferation of hematopoietic precursor

Hematopoietic stem cell Neutrophils Eosinophils Basophils Monocytes Platelets Red cells Myeloid progenitor Lymphoid progenitor Blymphocytes Tlymphocytes Plasma cells germinal center. Monoclonal Antibody Production. Method. Monoclonal Antibody Production technology was developed in 1975. Since its development it has been very important in the modern medical science with the diagnosis, therapy, research and even basic science today. It is still largely dependent upon animal testing however. Because it requires immunization of mice in order for them to create the antibodies to be grown. . Jung/. Shlush. Department . of Immunology. . Objectives of the seminar. Learn about the newest research the . . . hematopoetic. system and leukemia. Identify emerging topics and techniques. Christopher McNulty. Pittsburgh Central Catholic High School. Grade 11. PJAS 2011. Tissue Engineering. What is TE?. The development and manipulation. of artificial implants, laboratory-grown . tissues. Assist . Prof . Karima F. Ali. Al-mustansiriyah university. college of pharmacy. . Pharmaceutical chemistry. Monoclonal Antibodies . Monoclonal antibodies.  (. mAb.  or . moAb. ) are . Hematopoietic. stem cell. Neutrophils. Eosinophils. Basophils. Monocytes. Platelets. Red cells. Myeloid. progenitor. Lymphoid. progenitor. B-lymphocytes. T-lymphocytes. Plasma. cells. germinal center. 27. Learning Objectives—Level I. At the end of this unit of study, the student should be able to:. Define . acute lymphoblastic leukemia . (. ALL. ) and . lymphoblastic lymphoma . (. LBL. ) and differentiate them from acute myeloid leukemia (AML).. 23. Learning Objectives—Level I. At the end of this unit of study, the student should be able to:. Define and differentiate the terms . neoplasm. and . malignant. and identify hematopoietic disorders that can be included in each category.. At the end of this unit of study, the student should be able to:. Describe the basic concepts of cell differentiation and maturation.. Compare and contrast the categories of hematopoietic precursor cells: hematopoietic stem cells, hematopoietic progenitor cells, and maturing cells, including proliferation and differentiation potential, morphology, and population size.. . antibodies. Polyclonal. . antibodies. PAbs. . are secreted by different B cell lineages . They are a . collection of immunoglobulin . molecules that react against a specific antigen, each . identifying a different . Sigma brand products are sold through Sigma-Aldrich, Inc. Sigma-Aldrich, Inc. warrants that its products conform to the information contained in this and other Sigma-Aldrich publicationmust determine Introduction to Leukemia. Definition. Historic Perspective. Etiology and Risk Factors . Incidence. Classification. Comparison of Acute and Chronic Leukemia. Leukemia. Definition. Leukemia is a malignant disease of hematopoietic tissue characterized by the accumulation abnormal white cells (neoplastic or leukemic) in the bone marrow leading to bone marrow failure, a raised circulating white cell count (leukocytosis) and infiltrate organs (e.g liver, spleen, lymph nodes, brain) . neoplasms. Uncontrolled . proliferation and . decreased apoptotic . activity with variable degrees of differentiation . Composed of relatively mature . cells. Indolent. . (. If . untreated, the course is in months . CONSULTANT HAEMATOLOGIST . HEAD OF HAEMATOLOGY DIVISION. DEPARTMENT OF PATHOLOGY. Heterogeneous group of hematopoietic . neoplasms. Uncontrolled . proliferation and . decreased apoptotic . activity with variable degrees of differentiation . . A. ccumulation of abnormal blasts (. I. mmature precursors of WBC). . in bone marrow and blood leading to:. . 1- Bone marrow failure. . (. anemia ,neutropenia & thrombocytopenia). . 2- Organ infiltration .