PPT-Hematopoietic Stem Cell

Transplantation Apheresis and Mobilization Donna F erguson MD July 16 2015 History Overview Stem cell transplantation HPC Apheresis HPC Bone marrow Autologous Allogeneic Donor and recipient . Jung/. Shlush. Department . of Immunology. . Objectives of the seminar. Learn about the newest research the . . . hematopoetic. system and leukemia. Identify emerging topics and techniques. Location of Centers Participating. in the CIBMTR 2015. Annual Number of Transplant Recipients in the US by Transplant Type. Allogeneic Transplant Recipients in the US, by Donor Type. Cumulative Plot of Transplant Recipients in the US by Transplant Type. Location of Centers Participating. in the CIBMTR 2014. Annual Number of Transplant Recipients in the US by Transplant Type. Transplant Recipients in the US, by Transplant and Donor Type. Cumulative Plot of Transplant Recipients in the US by Transplant Type. Location of Centers Participating. in the CIBMTR 2013. Transplant Activity in the US. Allogeneic Stem Cell Sources by Recipient Age. Autologous Stem Cell Sources by Recipient Age. Trends in Transplants. Cell/Gene Therapy by: . Jeff Sheehy, the California Institute for Regenerative Medicine (CIRM). Jerome Zack, UCLA. Hans-Peter . Kiem. , The Fred Hutchinson Cancer Research Center. Jessica . Handibode. Ricerche. . Genetiche. e . Biomediche. (IRGB)/CNR. and . Humanitas Research Center. Pavia, . February. 29. th. , 2016. 1. Induced. . pluripotent. . stem. . (. iPS. ) . cells. iPSc. are . obtained by reprogramming . D. Craig Hooper, PhD, FNAI. Professor of Cancer Biology, SKCC, TJU. DouglasC.Hooper@Jefferson.edu. Therapeutic Modalities. Cancer immunotherapy. Hematologic disorders (non-malignant). Regenerative medicine. 23. Learning Objectives—Level I. At the end of this unit of study, the student should be able to:. Define and differentiate the terms . neoplasm. and . malignant. and identify hematopoietic disorders that can be included in each category.. At the end of this unit of study, the student should be able to:. Describe the basic concepts of cell differentiation and maturation.. Compare and contrast the categories of hematopoietic precursor cells: hematopoietic stem cells, hematopoietic progenitor cells, and maturing cells, including proliferation and differentiation potential, morphology, and population size.. A Pediatric Transplant Infectious Diseases Learning Module. Using the Modules. The modules are case-based, with decision points (branches) containing questions. Many questions don’t have right or wrong answers. Dr. Ali Khazaal Jumaa. F.I.B.M.S (Int. Medicine) , F.I.B.M.S (hematology). Definition :. Hematopoietic . stem cell transplantation (HSCT) involves the intravenous infusion of . autologous. or . allogeneic. BIOETHICS. STEM CELLS. A. . stem cell . is an immature cell capable of rapid division, self-renewal and development into specialized cells of the body.. Stem cells, having received signals from regulatory systems about some kind of “malfunction”, rush to the affected organ through the blood. Allografts. . transplantation of organs from one individual to another of the same species.. Rejection. is a complex phenomenon involving both cell- and antibody-mediated reactions that destroy the graft.. Def: the administration of hematopoietic stem cells from any source (ex: bone marrow, peripheral blood, umbilical cord blood) to reconstitute the bone marrow.. The Nobel Prize, 1990. E. Donnall Thomas .