Hematopoietic Stem Cells HSCs are capable of developing into any blood cell lineage They develop in the bone marrow A small percentage of HSCs interacted with the endosteal niche SNO cells and osteoblasts ID: 1042312
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1. Bone Marrow Niche Development of Hematopoietic Stem Cells®Hematopoietic Stem Cells (HSCs) are capable of developing into any blood cell lineage. They develop in the bone marrow.A small percentage of HSCs interacted with the endosteal niche, SNO cells, and osteoblasts.A majority of HSCs were sustained by the Reticular Niche, its CAR cells (see notes), and factors like CXCL12 and SCF.Adapted from: Sugiyama, T. and Nagasawa, T. 2012. Inflamm. Allergy Drug Targets. 11:201.