PPT-Hematopoietic malignancies

Myeloid Lymphoid Histiocytic Myeloid neoplasms 1 Myeloproliferative neoplasms 2 Myelodysplastic syndromes 3 Acute myeloid leukemia Features Recurrent genetic mutations Increased bone marrow cellularity. Educational Objectives. Minimal Residual Disease. Flow Cytometry. MRD Sensitivity Using Flow Cytometry. By Disease State. Genetic Methods for MRD Quantification. Allele-Specific Oligonucleotide (ASO)-PCR. Learning Goals. Immunotherapies in B-Cell Malignancies. Available Immunotherapies. OS in MM. Poor Outcome in High-Risk Myeloma. Immunotherapy. Potential for Success Without a Targetable Molecular Mutation. Changes made in 2014. Starting in 2014, there will be only one Hematopoietic Database. It will cover all of the hematopoietic diseases diagnosed from Jan. 1, 2010 forward.. Although there were changes to the MP rules, SEER is . Transplantation . Apheresis and Mobilization . Donna . F. erguson, M.D.. July 16, 2015. History . Overview. Stem cell transplantation . HPC, Apheresis . HPC, Bone marrow . Autologous . Allogeneic . Donor and recipient . Ricerche. . Genetiche. e . Biomediche. (IRGB)/CNR. and . Humanitas Research Center. Pavia, . February. 29. th. , 2016. 1. Induced. . pluripotent. . stem. . (. iPS. ) . cells. iPSc. are . obtained by reprogramming . Hematopoietic. stem cell. Neutrophils. Eosinophils. Basophils. Monocytes. Platelets. Red cells. Myeloid. progenitor. Lymphoid. progenitor. B-lymphocytes. T-lymphocytes. Plasma. cells. germinal center. Hematopoietic. stem cell. Neutrophils. Eosinophils. Basophils. Monocytes. Platelets. Red cells. Myeloid. progenitor. Lymphoid. progenitor. B-lymphocytes. T-lymphocytes. Plasma. cells. germinal center. June 28, 2018. Management of hematologic malignancies in older patients. Disclosures. for Tanya Wildes. Honorarium. Carevive. Systems. Research Funding. Janssen. Key issues (1). Are the considerations in older adults with hematologic malignancies different than in solid tumors?. 23. Learning Objectives—Level I. At the end of this unit of study, the student should be able to:. Define and differentiate the terms . neoplasm. and . malignant. and identify hematopoietic disorders that can be included in each category.. At the end of this unit of study, the student should be able to:. Describe the basic concepts of cell differentiation and maturation.. Compare and contrast the categories of hematopoietic precursor cells: hematopoietic stem cells, hematopoietic progenitor cells, and maturing cells, including proliferation and differentiation potential, morphology, and population size.. After receiving a request from the WTC Clinical Centers of Excellence to review certain myeloid disorders in terms of their status as malignancies, 1 the WTC Health Program has determined that, 2 e g A Pediatric Transplant Infectious Diseases Learning Module. Using the Modules. The modules are case-based, with decision points (branches) containing questions. Many questions don’t have right or wrong answers. Koopmansch. , Benjamin; . Palmeira. , . Leonor. , . Charloteaux. , Benoit; Lambert, Frédéric. Department. of . Human. . Genetics. , CHU . Liege. . 4000. . Liege. . . Belgium. .. In the frame of the development of new analytical methods for the diagnostic of patients suffering of suspected inherited malignancies with poor access to rapid diagnosis due to a restricted number of analytical sites or the current use of non-comprehensive targeted panels, we . Def: the administration of hematopoietic stem cells from any source (ex: bone marrow, peripheral blood, umbilical cord blood) to reconstitute the bone marrow.. The Nobel Prize, 1990. E. Donnall Thomas .