PPT-Stem cell transplantation

Contents History of HSCT First successful bone marrow transplant 1956 Dr E Donnall Thomas in New York Patient leukaemia Donoridentical twin The Nobel Prize 1990 E Donnall Thomas . Dr. Mustafa CETIN. 2. 5. th. . November. 201. 6. . . After the atomic bomb explosion in Japan, ending WW2, many scientists began to explore ways of protecting humans from irradiation. . How haematopoietic stem cell transplant was born:. -occlusive disease (VOD). Haematopoietic stem cell transplantation. Pathophysiology of VOD. Diagnosis of VOD. Assessment and management . of VOD. VOD case studies. Contents. Module 1: Haematopoietic stem cell transplantation. Describe some of the practical applications of reproductive cloning and the process and goals of therapeutic cloning.. CLONING OF PLANTS AND ANIMALS. 11.12-11.14. 11.12 Plant cloning shows that differentiated cells may retain all of their genetic potential. Learning objectives. To understand the difference between allogeneic and autologous HSCT. To understand the types of and reasons for the different HSCT conditioning regimens. To recognise potential complications associated with HSCT. Transplantation . Apheresis and Mobilization . Donna . F. erguson, M.D.. July 16, 2015. History . Overview. Stem cell transplantation . HPC, Apheresis . HPC, Bone marrow . Autologous . Allogeneic . Donor and recipient . Present. . and. . Future. Mustafa CETIN. ,. . MD . December. ,. . 2016. Erciyes University BMT Center. KHUH . , Doctor . Education Program. Passweg . et al. . BMT Feb. . 2016. ASCT in . Europe (2014. Ivetta Danylesko, MD. Department of Bone Marrow. . Transplantation. Chaim Sheba Medical Center, Tel-. Hashomer. History. HSCT was first explored in humans in the 1950s and was based on observational studies in mice models which showed that infusion of healthy bone marrow components into a . A stem cell is . a . “blank” cell. It can divide and produce identical . . copies – Self Renewal . P. rocess. Serves as a built-in repair system for . . . human . body. What Stem Cell does?. Exposure. Dr David J Heslop. Radiation Hazards. Non-ionising:. Electromagnetic spectrum. Ionising:. Alpha. Beta. Gamma. Neutron. X-radiation. Routes of Exposure. Direct exposure (line of sight). Secondary exposure:. Dr. Ali Khazaal Jumaa. F.I.B.M.S (Int. Medicine) , F.I.B.M.S (hematology). Definition :. Hematopoietic . stem cell transplantation (HSCT) involves the intravenous infusion of . autologous. or . allogeneic. Basic and applied implications. John S. Pixley, M.D. .. Associate Professor and Director, . Rheumatology / Immunology Division. UNSOM and. Chief, Rheumatology Section . VA Sierra Health Care System. . An Educational Slide Set . American Society of Hematology 2021 Guidelines for Sickle Cell Disease  Stem Cell Transplantation. Slide Set Authors: . Akshay Sharma, MBBS. , St. Jude Children’s Research Hospital, Memphis, TN and . Allografts. . transplantation of organs from one individual to another of the same species.. Rejection. is a complex phenomenon involving both cell- and antibody-mediated reactions that destroy the graft.. Def: the administration of hematopoietic stem cells from any source (ex: bone marrow, peripheral blood, umbilical cord blood) to reconstitute the bone marrow.. The Nobel Prize, 1990. E. Donnall Thomas .