PPT-Introduction to Hematopoietic Neoplasms

23 Learning ObjectivesLevel I At the end of this unit of study the student should be able to Define and differentiate the terms neoplasm and malignant and identify hematopoietic disorders that can be included in each category. of. Benign Neoplasms. Juan F. Yepes, DDS, MD, MPH. Assistant Professor. Department of Diagnostic Radiology. University of Kentucky Chandler Medical Center. The Radiology of Benign Neoplasms. Well defined. Neoplasm (neo=. new,plasm. =growth). Tumors may be defined as swelling or as a neoplasm. Remember Not all neoplasms form tumors.. Ex: Leukemia (. Leuk. =white, . emia. =blood) is a malignant disease of the bone marrow that causes an increase in white blood cells and might not form distinctive tumors.. normal cervical squamous epithelium.  at the left, but . dysplastic squamous epithelium.  at the right. Dysplasia is a disorderly growth of epithelium, but still confined to the epithelium. Dysplasia is still reversible.. Angela Fleischman . Division of hematology/Oncology. MPN are clonal disorders of the hematopoietic stem cell. Myelofibrosis. (MF). Hematopoietic stem cell . (HSC). Essential . Thrombocythemia. (ET). Changes made in 2014. Starting in 2014, there will be only one Hematopoietic Database. It will cover all of the hematopoietic diseases diagnosed from Jan. 1, 2010 forward.. Although there were changes to the MP rules, SEER is . normal cervical squamous epithelium.  at the left, but . dysplastic squamous epithelium.  at the right. Dysplasia is a disorderly growth of epithelium, but still confined to the epithelium. Dysplasia is still reversible.. Transplantation . Apheresis and Mobilization . Donna . F. erguson, M.D.. July 16, 2015. History . Overview. Stem cell transplantation . HPC, Apheresis . HPC, Bone marrow . Autologous . Allogeneic . Donor and recipient . Ricerche. . Genetiche. e . Biomediche. (IRGB)/CNR. and . Humanitas Research Center. Pavia, . February. 29. th. , 2016. 1. Induced. . pluripotent. . stem. . (. iPS. ) . cells. iPSc. are . obtained by reprogramming . characterised . by . overproduction of one or more myeloid cell types . via bone marrow stimulation. . Entities include;. Polycythaemia vera, (PV). Essential . thrombocythaemia . (ET). Primary . (idiopathic) . At the end of this unit of study, the student should be able to:. Describe the basic concepts of cell differentiation and maturation.. Compare and contrast the categories of hematopoietic precursor cells: hematopoietic stem cells, hematopoietic progenitor cells, and maturing cells, including proliferation and differentiation potential, morphology, and population size.. After receiving a request from the WTC Clinical Centers of Excellence to review certain myeloid disorders in terms of their status as malignancies, 1 the WTC Health Program has determined that, 2 e g A Pediatric Transplant Infectious Diseases Learning Module. Using the Modules. The modules are case-based, with decision points (branches) containing questions. Many questions don’t have right or wrong answers. Myeloid. Lymphoid. Histiocytic. Myeloid . neoplasms. (1) . Myeloproliferative. . neoplasms. (2) . Myelodysplastic. syndromes. (3) Acute myeloid leukemia. Features:. Recurrent genetic mutations. Increased bone marrow cellularity. Def: the administration of hematopoietic stem cells from any source (ex: bone marrow, peripheral blood, umbilical cord blood) to reconstitute the bone marrow.. The Nobel Prize, 1990. E. Donnall Thomas .