PPT-Introduction to Hematopoietic Neoplasms

23 Learning ObjectivesLevel I At the end of this unit of study the student should be able to Define and differentiate the terms neoplasm and malignant and identify hematopoietic disorders that can be included in each category. Module: CNS Neoplasms Copyright Adapted from {. Gazit. R, . Weissman. IL and Rossi DJ 2008}. HSC. MPP. Mouse. Lineage. -/low. Sca1. +. cKit. +. flk2. -. CD34. -. CD48. -. CD150. +. Human. Lineage. -/low. CD90. +. CD45RA. -. CD34. Learning Objectives (1 of 2). Describe composition and functions of blood, and functions of the lymphatic system. Explain classification of anemia. List and describe causes and treatment of hypochromic microcytic anemia and macrocytic anemia . Changes made in 2014. Starting in 2014, there will be only one Hematopoietic Database. It will cover all of the hematopoietic diseases diagnosed from Jan. 1, 2010 forward.. Although there were changes to the MP rules, SEER is . normal cervical squamous epithelium.  at the left, but . dysplastic squamous epithelium.  at the right. Dysplasia is a disorderly growth of epithelium, but still confined to the epithelium. Dysplasia is still reversible.. Location of Centers Participating. in the CIBMTR 2015. Annual Number of Transplant Recipients in the US by Transplant Type. Allogeneic Transplant Recipients in the US, by Donor Type. Cumulative Plot of Transplant Recipients in the US by Transplant Type. Transplantation . Apheresis and Mobilization . Donna . F. erguson, M.D.. July 16, 2015. History . Overview. Stem cell transplantation . HPC, Apheresis . HPC, Bone marrow . Autologous . Allogeneic . Donor and recipient . Chapter 14 The Hematopoietic and Lymphatic Systems Learning Objectives (1 of 2) Describe composition and functions of blood, and functions of the lymphatic system Explain classification of anemia List and describe causes and treatment of hypochromic microcytic anemia and macrocytic anemia Cell/Gene Therapy by: . Jeff Sheehy, the California Institute for Regenerative Medicine (CIRM). Jerome Zack, UCLA. Hans-Peter . Kiem. , The Fred Hutchinson Cancer Research Center. Jessica . Handibode. Ricerche. . Genetiche. e . Biomediche. (IRGB)/CNR. and . Humanitas Research Center. Pavia, . February. 29. th. , 2016. 1. Induced. . pluripotent. . stem. . (. iPS. ) . cells. iPSc. are . obtained by reprogramming . characterised . by . overproduction of one or more myeloid cell types . via bone marrow stimulation. . Entities include;. Polycythaemia vera, (PV). Essential . thrombocythaemia . (ET). Primary . (idiopathic) . After receiving a request from the WTC Clinical Centers of Excellence to review certain myeloid disorders in terms of their status as malignancies, 1 the WTC Health Program has determined that, 2 e g A Pediatric Transplant Infectious Diseases Learning Module. Using the Modules. The modules are case-based, with decision points (branches) containing questions. Many questions don’t have right or wrong answers. Myeloid. Lymphoid. Histiocytic. Myeloid . neoplasms. (1) . Myeloproliferative. . neoplasms. (2) . Myelodysplastic. syndromes. (3) Acute myeloid leukemia. Features:. Recurrent genetic mutations. Increased bone marrow cellularity.