PPT-Primary craniocerebral vasculitis

Takayasus arteritis giant cell arteritis and primary CNS angiitis all have granulomatous angiitis Takayasus arteritis This affects the aortic arch main arterial trunks and descending aorta including the carotid and subclavian arteries. (. Grace). Melanie Kong. Jeremy Ng. Tina Ngo. Causes and Treatment of Granulomatosis with . Polyangiitis. PHM142H1. October 11, 2016. PHM142 Fall . 2016. Coordinator. : Dr. Jeffrey Henderson. Instructor: Dr. David Hampson. History. Middle. -aged, . right handed Caucasian . male . no . home medications, no . PMH. Three week history of low grade fever and frontal headache. Diagnosed by PCP as sinus infection and given antibiotics . . Rheumatica,Giant. Cell . Arteritis. , Wegener’s . Granulomatosis. , . Polyarteritis. . Nodosa. What is . Vasculitis. ?. Disease characterized by inflammation of blood vessel walls, leading to altered blood flow through obstructed walls. This causes ischemia and tissue damage. . By: Dr. Donna Braham. Objectives. Classify Vasculitis. Know when to consider Vasculitis. Rule out mimickers of Vasculitis. Diagnose cutaneous small vessel vasculitis – In . particular Henoch–. Schönlein. Prof. Dr. Gamze MOCAN KUZEY. NEU. Department of Pathology. Vascular Lesions. Atherosclerosis. Arteriolosclerosis. Varicose veins. Trombophlebitis. Lymphedema. Aneurysms. Dissection. Vasculitis. Vasculitis. The clinical features of the various . vasculitides. are protean and largely depend on the vascular bed affected (e.g., CNS vs. heart vs. small bowel). . Besides the findings referable to the specific tissues involved, the clinical manifestations typically include constitutional signs and symptoms such as fever, . aortitis. ?. Emily Grodinsky. 11.5.2020. Categorizing vessels by size. More on primary vasculitidities. Even diseases like GCA/. Takayasu. arteritis have significant effects from the smaller vessels (e.g., ophthalmic or retinal arteries in GCA leading to significant morbidity, despite not being “large vessels”). Signs and symptoms:. 1- . local. :. according. to the involved tissue. 2- . systemic. :(fever, . myalgia. , . arthralgias. , and malaise). Pathogenesis . 1- immune-mediated inflammation. . 2- . infectious pathogens. CABM FIBMS. Internist & Rheumatologist. Large Vessel Vasculitis . Takayasu arteritis. Mikito Takayasu (. 1860.  . - 1938)  . Japanese ophthalmologist. CLINICAL FEATURES . . Diagnosis. . By angiography, which reveals Coarctation, occlusion &aneurysmal dilatation. . Vasculopathy. Fibrinoid deposition, thrombosis with limited to no inflammation.. Infiltration of vessel wall by inflammatory cells with otherwise minimal alteration.. Leukocytoclasis. of tissue infiltrate with minimal alteration of vessel, that is, swelling only, absence of fibrinoid. PRESENTER- Dr. B. PRADEEP.. CHAIR PERSON- Dr. T. SMRUTHI.. Vasculitis are group of disorders characterized by . immunoinflammatory. injury to vessel wall . leading to aneurysm, bleeding, stenosis, occlusion, thrombosis, embolism and ischemia. . Results of the Vasculitis Patient-Powered Research Network Sleep Study (. SleepVasc. ) . . Misa Tanaka. 1. , Osvaldo . Espin. Garcia. 1. , Kathy Speechley. 1. , . Saverio. Stranges. 1. , Molly Mason. 2. , Dianne G Shaw. 3. , Kalen Larson. 3. , Cristina Burroughs. 4. , . and . Peter A. Merkel. 5. , . for . the Vasculitis Patient-Powered Research Network . 1. University of California Los Angeles, Los Angeles, CA, USA; . aortitis. ?. Emily Grodinsky. 11.5.2020. Categorizing vessels by size. More on primary vasculitidities. Even diseases like GCA/. Takayasu. arteritis have significant effects from the smaller vessels (e.g., ophthalmic or retinal arteries in GCA...