PPT-Anemia/Erythrocyte Disorders

Laboratory Procedures Anemia Defined A condition of reduced oxygen carrying capacity of erythrocytes Erythrocyte disorders May be associated with Decreased production of RBCs Increased destruction of . Chapter 11. Medical Considerations. Hyperpituitarism. Excess hormone production by the anterior pituitary gland. Caused most often by a benign tumor (pituitary adenoma) that produces growth hormone. Giantism. Shelby Engel and Sarah . Heins. . Blood transports necessary nutrients and hormones. Color, volume, viscosity, and . pH. RBCs/erythrocytes – transport oxygen. 4.2-6.3 million live 120 days. Hemoglobin typically 13.5-18g/100 ml for males, 12-16 for females. Hematology. Lab 2. RBC’s Morphology. RBCs Abnormal morphology. Peripheral Blood Morphology. Abnormal erythrocyte morphology. Is found in pathological states that may be abnormalities in . Red cell distribution.. Read through these in your notes and in your text to make sure you understand the causes and/or symptoms . They will be on your Quiz. Hemolytic anemia. Aplastic Anemia. Thalassemia. Sickle Cell Anemia. Introduction. Epidemiology . Drug-induced Aplastic anemia. Drug-induced Hemolytic anemia. Drug-induced Neutropenia and Agranulocytosis. Drug-induced Thrombocytopenia. Drug-induced Megaloblastic anemia. CP Biology. Genetic Disorders. Major types of genetic disorders:. Autosomal. Single genes. Multiple genes. Sex-linked. Chromosome abnormalities. Autosomal Disorders. Autosomal genetic disorders . are caused by alleles on autosomes (chromosomes other than the sex chromosomes). . Igor Theurl1–3,17, Ingo Hilgendorf1,2,4,17, Manfred Nairz1,2,17, Piotr Tymoszuk3, David Haschka3, Malte Asshoff3, Shun He1,2, Louisa M S Gerhardt1,2, Tobias A W Holderried5, Markus Seifert3, Sieghart Sopper6, Ashley M Fenn1,2, Atsushi Anzai1,2, Sara Rattik1,2, Cameron McAlpine1,2, Milan Theurl7, Peter Wieghofer8,9, Yoshiko Iwamoto1,2, Georg F Weber1,2, Nina K Harder1,2, Benjamin G Chousterman1,2, Tara L Arvedson10, Mary McKee1,11, . . Igor Theurl1–3,17, Ingo Hilgendorf1,2,4,17, Manfred Nairz1,2,17, Piotr Tymoszuk3, David Haschka3, Malte Asshoff3, Shun He1,2, Louisa M S Gerhardt1,2, Tobias A W Holderried5, Markus Seifert3, Sieghart Sopper6, Ashley M Fenn1,2, Atsushi Anzai1,2, Sara Rattik1,2, Cameron McAlpine1,2, Milan Theurl7, Peter Wieghofer8,9, Yoshiko Iwamoto1,2, Georg F Weber1,2, Nina K Harder1,2, Benjamin G Chousterman1,2, Tara L Arvedson10, Mary McKee1,11, . “Anemia”. . Dr. Sabin Thomas, M. Pharm. Ph. D.. Assistant . Professor. in . Pharmacy. Practice. School. of . Pharmacy. , CPN. University. of Nizwa. University of Nizwa. College of Pharmacy and Nursing. Assistant lecturer: Shahad . S.aldeen. . Department of pharmacology and toxicology . May-2021. Hematotoxicology. Hematotoxicology is the study of adverse effects of drugs, chemicals, on blood and blood-forming tissues.. 1- what is the mode of inheritance in the vast majority f spherocytosis cases?. Autosomal dominant. Autosomal recessive. X-linked dominant. X linked recessive. 2- The amino acid present at the sixth position of the normal alpha-globin chain is replaced by which one of the following amino acids in sickle cell disease?. At the end of this unit of study, the student should be able to:. List and describe the stages of erythrocyte maturation in the marrow from youngest to most mature cells.. Explain the maturation process of reticulocytes and the cellular changes that take place.. Anemia. True or absolute anemia is defined as a decrease in erythrocyte mass within the body. HCT, hemoglobin, and RBC count values are usually below their reference intervals.. Low erythrocyte parameters may also be present in blood when the total-body erythrocyte mass is normal (relative anemia). . doi: 10.5505/kjms.2019.67934 Ergn Takn, Kaas Ünverstes, Tp Fakültes Dekanlk Bnas, B114, Kars, Türkye Tel: of 658 patients were inc