Handling and Transportation of Vaccines Adapted from the FAD PReP NAHEMS Guidelines Vaccination for Contagious Diseases 2014 Vaccine handling and storage Vaccine packaging and transport ID: 477611
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Slide1
Vaccination for Contagious Diseases
Handling and Transportation of Vaccines
Adapted from the FAD
PReP
/NAHEMS
Guidelines: Vaccination for Contagious Diseases (
2014)Slide2
Vaccine handling and storage
Vaccine packaging and transportCold Chain monitorsPreparation of lyophilized
vaccine
Maintenance of sterility
USDA APHIS and CFSPH
FAD PReP/NAHEMS Guidelines: Vaccination for Contagious Diseases - Handling
This PresentationSlide3
Vaccine Handling
USDA APHIS and CFSPH
FAD
PReP
/NAHEMS Guidelines: Vaccination for Contagious Diseases - HandlingSlide4
Protect the potency and safety
Maintain the cold chainNarrow temp rangeDuring storage, transport, and handling
Lyophilized
vaccineReconstitute only with diluent provided
Maintain sterilityUSDA APHIS and CFSPH
FAD PReP/NAHEMS Guidelines: Vaccination for Contagious Diseases - Handling
Vaccine HandlingSlide5
Vaccine Storage
USDA APHIS and CFSPH
FAD
PReP
/NAHEMS Guidelines: Vaccination for Contagious Diseases - HandlingSlide6
Most require either refrigeration or freezing
Dedicated unitsEnsure temperature rangeMonitor
and record
temperatureDo not subject to freeze-thaw cycles
USDA APHIS and CFSPH
FAD PReP/NAHEMS Guidelines: Vaccination for Contagious Diseases - HandlingVaccine StorageSlide7
Vaccines requiring a storage temperature of 35 to 46°F
Standard household or commercial refrigeratorVaccines requiring a storage of 5° FStandard or commercial freezer
Dormitory-style refrigerators
are not acceptable for long term storage
USDA APHIS and CFSPH
FAD PReP/NAHEMS Guidelines: Vaccination for Contagious Diseases - HandlingVaccine Storage Slide8
Do not store vaccines in door or vegetable bin
Do not overfill cooling unitAvoid impeding cold air circulationProtect from
light
USDA APHIS and CFSPH
FAD
PReP/NAHEMS Guidelines: Vaccination for Contagious Diseases - HandlingVaccine Storage Slide9
Limit door opening
Properly close/seal doorsAvoid on/off switch“Do not unplug” sign by the outlet
Emergency back-up
powerTemperature alarm
USDA APHIS and CFSPH
FAD PReP/NAHEMS Guidelines: Vaccination for Contagious Diseases - HandlingVaccine Storage Slide10
Packaging Vaccine for Transport
USDA APHIS and CFSPH
FAD
PReP
/NAHEMS Guidelines: Vaccination for Contagious Diseases - HandlingSlide11
To package a vaccine for transport:
1. Delay opening refrigerator or freezer until all preparations are made2. Pack refrigerated vaccines first
3. Use properly insulated containers
USDA APHIS and CFSPH
FAD
PReP/NAHEMS Guidelines: Vaccination for Contagious Diseases - HandlingVaccine Packaging Slide12
4. Include enough packs to maintain the cold chain
5. Place insulating barrier between refrigerated/frozen packs and vaccines
Bubble wrap, paper, Styrofoam peanuts
Properly layer contents in container
USDA APHIS and CFSPHFAD
PReP/NAHEMS Guidelines: Vaccination for Contagious Diseases - HandlingVaccine PackagingSlide13
6. Ship vaccines in original packaging
7. Thermometer or cold chain device should be placed next to vaccines8. Note the packing time on outside of package
USDA APHIS and CFSPH
FAD
PReP/NAHEMS Guidelines: Vaccination for Contagious Diseases - Handling
Vaccine PackagingSlide14
9. Clearly identify the contents as fragile and perishable on the outside of package
10. If travelling by car stow the packed vaccines in the passenger compartment, not in the trunk
USDA APHIS and CFSPH
FAD
PReP/NAHEMS Guidelines: Vaccination for Contagious Diseases - Handling
Vaccine Packaging Slide15
Vaccine Transport
USDA APHIS and CFSPH
FAD PReP/NAHEMS Guidelines: Vaccination for Contagious Diseases - HandlingSlide16
Minimize the number of times a vaccine is transported
Check or monitor the temperatureDiluents should always travel with corresponding vaccines
USDA APHIS and CFSPH
FAD
PReP/NAHEMS Guidelines: Vaccination for Contagious Diseases - Handling
Vaccine TransportSlide17
Inspect upon arrival
Check for physical damageCheck expiration datesEnsure proper diluent was shipped
Inspect cold chain monitors, if included
USDA APHIS and CFSPH
FAD PReP
/NAHEMS Guidelines: Vaccination for Contagious Diseases - HandlingVaccine TransportSlide18
Cold Chain
Monitors USDA APHIS and CFSPH
FAD
PReP
/NAHEMS Guidelines: Vaccination for Contagious Diseases - HandlingSlide19
Intended for a single use, not over 48 hours
Will indicateIf temperature was over 50°FHow long temperature was over 50°F
USDA APHIS and CFSPH
FAD
PReP/NAHEMS Guidelines: Vaccination for Contagious Diseases - Handling
Heat IndicatorsSlide20
Intended for a single useDo not indicate length of time items exposed to freezing temperatures
Indicate temperature has dropped below 32°F (0°C)
USDA APHIS and CFSPH
FAD
PReP/NAHEMS Guidelines: Vaccination for Contagious Diseases - Handling
Freeze Indicators Slide21
Any indication that proper temperature has not been maintained:
Mark the vaccine “DO NOT USE”Contact supervisor or other authority for further instructionsDo NOT immediately discard the vaccine unless directed to do so
USDA APHIS and CFSPH
FAD
PReP
/NAHEMS Guidelines: Vaccination for Contagious Diseases - HandlingIf the Cold Chain is BrokenSlide22
Preparing to Administer Lyophilized Vaccine
USDA APHIS and CFSPH
FAD
PReP
/NAHEMS Guidelines: Vaccination for Contagious Diseases - HandlingSlide23
Reconstitute with diluentDiluent is NOT interchangeable
Use diluent specified for vaccineDiluents that do not require refrigeration can be stored in areas of the refrigerator that are not suitable for vaccine storage
USDA APHIS and CFSPH
FAD
PReP/NAHEMS Guidelines: Vaccination for Contagious Diseases - Handling
Lyophilized VaccinesSlide24
Reconstitute immediately prior to use
Check expiration date and match lot numbersMark vial with date of reconstitution
Transfer diluent with sterile needle and syringe
Administer promptly using new needle
USDA APHIS and CFSPHFAD
PReP/NAHEMS Guidelines: Vaccination for Contagious Diseases - HandlingReconstituting VaccinesSlide25
Maintaining Sterility
USDA APHIS and CFSPH
FAD PReP/NAHEMS Guidelines: Vaccination for Contagious Diseases - HandlingSlide26
To maintain sterility in multi-dose vials:
Practice sterile techniqueNever remove rubber stopperWipe stopper before piercing
Use a new sterile needle each time
Use ice packs to keep vaccines cool; do not submerge in water
USDA APHIS and CFSPH
FAD PReP/NAHEMS Guidelines: Vaccination for Contagious Diseases - HandlingMaintaining Sterility Slide27
Always mark multi dose vaccines with:
Date opened or reconstitutedInitials of the user Dating the vials will help identifyWhich vials should be used first
Which vials should be discarded
USDA APHIS and CFSPH
FAD
PReP/NAHEMS Guidelines: Vaccination for Contagious Diseases - HandlingMaintaining SterilitySlide28
Individual requirements varyRefer to manufacturer’s recommendations
Proper handling is critical to protect potency and safety May be no detectible changes if vaccine has been damaged
USDA APHIS and CFSPH
FAD PReP/NAHEMS Guidelines: Vaccination for Contagious Diseases - Handling
Vaccine Handling SummarySlide29
FAD
PReP/NAHEMS Guidelines: Vaccination for Contagious Diseaseshttp://
www.aphis.usda.gov/fadprep
Vaccination
for Contagious Diseases web-base training modulehttp://naherc.sws.iastate.edu/
USDA APHIS and CFSPHFAD PReP/NAHEMS Guidelines: Vaccination for Contagious Diseases - Handling
For More InformationSlide30
Authors (CFSPH)
Jim Roth, DVM, PhD, DACVMAmber
Stumbaugh
, MSAnna Rovid-Spickler
, DVM, PhDDanelle Bickett-Weddle, DVM, MPH, PhD, DACVPMJanice Mogan, DVMHeather Allen, PhD, MPAShaine
DeVoeReviewers (USDA) John Zack, DVMPatricia Foley, DVM, PhDR. Alex Thompson, DVM, PhDJohn
Wiemers
, DVM, MS
USDA APHIS and CFSPH
FAD
PReP
/NAHEMS Guidelines: Vaccination for Contagious Diseases - Handling
Guidelines ContentSlide31
Acknowledgments
Development of this presentation was by the Center for Food Security and Public Health at Iowa State University through funding from
the
USDA APHIS
Veterinary Services
PPT Author: Patricia Futoma, Veterinary Student
Reviewers: Cheryl L. Eia, JD, DVM, MPH; Janice Mogan, DVM