PPT-INFLAMMATION DR.AYSER HAMEED

LEC1 General Features Inflammation is defined as the response of living vascularized tissues to harmful agents It consists principally of vascular changes associated with leukocytes infiltration and systemic reactions. Team JEEVES. Daniel . Steffy. , . Alissa. Halvorson, . Bogdan. . Pisica. , Christopher Pearson, . Hameed. . Ebadi. A Beacon-Sensing, Path Finding Robot Operating in a Crowded Environment. Current Status. . classification of acute inflammation. :. according to the inflammatory fluid exudates, . -Exudates . are any fluid that filters from the circulatory system into lesions or areas of inflammation. 1- . Joseph Burdon + Tim . Sargeant. Inflammation. = . a localized physical condition in which part of the body becomes . reddened, swollen, hot, . and often . painful. , especially as a reaction to injury or infection.. Its purpose is to . localize. ,. . eliminate. the injurious . agent, . remove . damaged tissue . and . replace. it with healthy new tissue (. repair. ). . It consist principally of vascular changes associated with leukocyte infiltration and systemic reaction.. Kristen Dostie. April 8, 2015. Cadmium (Cd). Toxic heavy metal . Found naturally in environment. Extremely long biological half-life . of 18-33. . years. Intoxication leads to a variety of adverse effects. MSc . Etab. A. AL-. Mosawe. Fibrinous pericarditis.  is an exudative inflammation. The visceral pericardium (epicardium) is infiltrated by the fibrinous exudate. This consists in fibrin strands and leukocytes. Fibrin describes an eosinophilic (pink) network, amorphous. Leukocytes (. . Redha. AL-. Sabbagh. . definition . Acute. . inflammation. is a rapid host response that serves to deliver leukocytes and plasma proteins, such as antibodies, to sites of infection or tissue injury. LEC.2. Most benign tumors grow slowly . & most of cancers grow faster . & eventually spread locally & to distant sites (metastasis) & causing death.. In some exception, some benign tumors grow more rapidly than some cancers e.g. leiomyoma (uterine fibroid), which is benign smooth muscle tumor influence by estrogen & so increase in size during pregnancy.. LEC.3. Incidence of cancer. In male. . 30% Carcinoma of prostate. .. 14% Carcinoma of Lung.. 11% Carcinoma of colon & rectum.. In female. . . 31% breast carcinoma. .. 12% carcinoma of lung. . LEC.5. Chemical carcinogenesis:. General principles of chemical carcinogens;. I. . Could be . natural or synthetic chemical. ..  . II. . Chemicals either . direct acting chemical. (. active without transformation in the body). 1-Resolution: . restoration. to . histologic. and . functional. . normalcy. :. -. Neutralization. or . removal. of the various . chemical mediator. s. .. -. N. ormalization. . of vascular . permeability. 1 IN THE HEALING PROCESS by Keith Wassung 2 The role of inflammation in the process of healing has been misunderstood for many years. Recent neurological and immunological research has shed light LEC.4. Carcinogenesis:. is a multistep process at both . phenotypic & genetic levels.. Phenotypic level . includes:. I. Excessive growth.. II. Local invasion.. III. Metastasis.. These three criteria are called collectively . LEC.5. 3. Evasion of apoptosis:. Normally, . the mechanism of . apoptosis is mediated by many genes, & achieve by two phases. . Initiation phase. , which is mediated by . TNF- Fas receptor . & inhibited by FLIP protein..