PPT-Inflammation Prof. Dr. Dalya Basil

Steps of inflammatory response 1 Recognition of injurious agent 2 Recruitment of leukocytes 3 Removal of the agent 4 Regulation of response 5 Resolution Acute Inflammation Acute inflammation is the early almost immediate reaction of local tissues and their blood vessels to injury . Acute And Chronic. The cardinal signs of inflammation. Vascular changes in the acute inflammatory process. Cellular changes in the acute inflammatory process. Peripheal. blood smear. Perhaps the simplest indicator of acute inflammation is an increase in the white blood cell count in the . GraphG prof 1 prof 2 prof 3 prof 4 phd 5 stud 6 stud 7 adv adv adv adv adv sup sup GraphI 1 prof 2,3 prof 4 prof 5 phd 6,7 stud adv adv adv sup 1Fortheformaldevelopmentinthispaper,itwillbeconve-nientt What is inflammation?. it’s a body response against ( MILD or MODERATE) injury , it’s a first line of defense. .. Not severe enough to cause cell death (necrosis).. . Inflammation is of two types:. Joseph Burdon + Tim . Sargeant. Inflammation. = . a localized physical condition in which part of the body becomes . reddened, swollen, hot, . and often . painful. , especially as a reaction to injury or infection.. Its purpose is to . localize. ,. . eliminate. the injurious . agent, . remove . damaged tissue . and . replace. it with healthy new tissue (. repair. ). . It consist principally of vascular changes associated with leukocyte infiltration and systemic reaction.. rubor. (redness), . calor. (heat), tumor (swelling), dolor (pain), and loss of function. Seen here is skin with . erythema. , compared to the more normal skin at the far right.. The arm at the bottom is swollen (edematous) and reddened (. MSc . Etab. A. AL-. Mosawe. Fibrinous pericarditis.  is an exudative inflammation. The visceral pericardium (epicardium) is infiltrated by the fibrinous exudate. This consists in fibrin strands and leukocytes. Fibrin describes an eosinophilic (pink) network, amorphous. Leukocytes (. . Redha. AL-. Sabbagh. . definition . Acute. . inflammation. is a rapid host response that serves to deliver leukocytes and plasma proteins, such as antibodies, to sites of infection or tissue injury. J. Matthew Velkey. matt.velkey@duke.edu. 454A Davison, Duke South (green zone). Cellular Adaptation to Injury or Stress. Injury or Stress. Increased demand. Decreased stimulation or lack of nutrients. Zeinab Ghorbani. Ph.D. Candidate in Nutritional Sciences, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS).. Introduction. Top 10 level-4 causes of disability in GBD 2016 (global, both sexes, all ages). Inflammation is a set of symptoms that include pain, swelling, heat, and redness of an affected organ or tissue. It is the natural way the body’s immune system responds to injury, infection or attack. 1-Resolution: . restoration. to . histologic. and . functional. . normalcy. :. -. Neutralization. or . removal. of the various . chemical mediator. s. .. -. N. ormalization. . of vascular . permeability. 1 IN THE HEALING PROCESS by Keith Wassung 2 The role of inflammation in the process of healing has been misunderstood for many years. Recent neurological and immunological research has shed light Cellular injury. Cellular injury . can occur in a number of different ways. The extent of injury that cells experience is often related to the intensity and duration of exposure to the injurious event or substance. Cellular injury may be a reversible process, in which case the cells can recover their normal function, or it may be irreversible and lead to cell death. .