PPT-Extracting Biological Information from Gene Lists

Simon Andrews Laura Biggins Boo Virk simonandrewsbabrahamacuk laurabigginsbabrahamacuk v202301 Programme The theory and practice of gene set enrichment Gene set enrichment practical. Ju. . Han Kim . Division of Biomedical Informatics, Seoul National University College of Medicine, Seoul, Korea, . Presenter: Zhen Gao . 2. Outline. Review of major computational . approaches to facilitate biological interpretation of . Implications for Neurodevelopment. . Clyde Hertzman, MD. Human Early Learning Partnership. University of British Columbia, Vancouver. Gradient in all Cause Mortality: . . UK Whitehall Study. CHD Mortality - UK Whitehall Study. Date. . :. . 2013/08/20. Source. . :. . SIGIR’13. Authors : . Weize. Kong and James . Allan. Advisor . : . Dr.Jia. -ling, . Koh. Speaker : . Wei, Chang. 1. Outline. Introduction. Approach. Experiment. Adam Stevens, Daniel Hanson, Andrew . Whatmore. , Benoit . Destenaves. , Pierre . Chatelain. , Peter . Clayton. Supplementary Information: . Introduction. In this Supplementary Information we make available additional data that were discussed in the main manuscript. . The term ‘Bioinformatics’ was first introduced in 1970 by . Paulien. . Hogeweg. . to refer to the study of information processes in biotic systems. While some people define the term as “. An integration of computer, mathematical and statistical methods to manage and analyze biological information. Jeffrey S. Morris. Del and Dennis McCarthy Distinguished Professor. Department of Biostatistics. The University of Texas M.D. Anderson Cancer Center. Big Data in Biomedical Research. Explosion of complex information-rich data has revolutionized biomedical research. dosimetry. Kamil Brzóska. Institute. of . Nuclear. . Chemistry. and Technology, . Centre for . Radiobiology. and . Biological. . Dosimetry. , . Warsaw. , Poland. What is biological . dosimetry. analysis - outliers. V2: batch effects. V3: data imputation. What . is measured by microarrays?. Microarray normalization. Differential gene expression (DE) analysis based on microarray data. Detection of outliers. Program for today. :. - . Have. all genes . been. . studied. . with. . the. same . intensity. ?. - . Functional. . annotation. . of. genes/. gene. . products. : Gene . Ontology. (GO. ). - . What is measured by microarrays?. Microarray normalization. Differential gene expression (DE) analysis based on microarray data. Detection of outliers. RNAseq. data. DE analysis based on . RNAseq. data. Program for today:. - . Functional. . annotation. . of. genes/. gene. . products. : Gene . Ontology. (GO). - . significance. . of. . annotations. : . hypergeometric. . test. - (. mathematical. SNP . frequencies in 1000 Genomes . data. Repeats in imprinted vs. . biallelically. expressed genes. Non-canonical translation. It is necessary to filter / clean the gene sets so that . the research question being addressed can be answered in the best way.. Section 8 – Controversial . Biological Procedures. We will be . learning to…. D. escribe what a controversial biological procedure is . Give examples of controversial biological procedures. Describe what gene therapy is. to . regulatory and interaction networks. October 23. rd. . – 25. th. , 2015. HSE – Nizhny Novgorod. Mario R. Guarracino. joint work with Marina . Piccirillo. , . Sonali. . Chavan. , . Parijat.