DNA Replication TranscriptionTranslation Video Title Translation Page 31 EQ How does Translation lead to the production of protein Date 1021 Central Dogma DNA mRNA Protein Translation ID: 1044163
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1. Day 08Warm Up- You and your partner will discuss DNA replication vs transcription after watching the 2 videos DNA ReplicationTranscription/Translation Video
2. Title: TranslationPage: 31EQ: How does Translation lead to the production of protein?Date: 10/21
3. Central DogmaDNAmRNAProteinTranslationTranscriptionNucleusRibosomeDealing with this part today!
4. Transcription Review and Translation Intro.
5. Translation:decoding of an mRNA message into a polypeptide(Protein) chain occurs on a ribosome (OUTSIDE the nucleus)
6. Translation:mRNA travels outside of the nucleus and connects to the ribosomeNucleusCytoplasm
7. 2. transfer RNA (tRNA) brings amino acids to the ribosomeAmino Acid
8. 3. The ribosome connects the amino acids to form a polypeptide chain (protein)Amino Acid (Monomer)Protein (Polymer)
9. How does tRNA “know” what amino acid to bring?
10. Codon:three consecutive mRNA basesEx: GCUAnticodon:three complementary tRNA basesCodonGCUCGAAnticodon
11. tRNA looks for the codon that pairs with its anticodon the ribosome takes the amino acid and attaches it to the polypeptide chainAmino AcidmRNAtRNAAnticodon
12. ORDER MATTERS!order of DNA bases order of RNA bases order of amino acids what protein is made tRNAmRNAAmino acids
13. How to use the Codon Chart:Use the left side to find the first letter in the codonUse the top to find the second letter in the codonUse the right side to find the third letter of the codonGo to where ALL three overlap on the chart
14.
15. Did you notice?: The codon “AUG” can specify methionine or serve as the “start” codon for protein synthesis.
16. How to use the Codon Wheel:Begin in the middle with the first letter of the codonGo outward to the second letter in the codonGo outward again to the third letter in the codon.
17. What other codons will tell the ribosome to stop putting amino acids together? What DNA sequences will give you these codes?
18. DNAmRNAtRNAAmino AcidAGGCGCGUCUCGAUCUCCGCGCAGAGCUAGFill in your mRNA strand from you DNAFill in your tRNA from your mRNACircle a CodonUse your Codon wheel or Chart to find your amino AcidArginineArginineValineSerineIsoleucine***Remember we use CODONS to read our CODON chart… not the anticodons. Anticodons just bring the correct amino acid.
19. Codon Bingo!Directions For Playing:If a codon (example: AAG) is called out, you must find the amino acid.If an amino acid (example: serine) is called out, you must find the codon.Hint! When finding a codon, there may be more than one answer…you can count all possible answers on your card!