PPT-ARC Linkage 2014 – Session 1 - Overview, Tips and Hints

Rose Firkin Executive Officer Deakin Research Grants Greg Pullen Senior Commercial Manager Deakin Research Commercial Outline Revised NCG process Main features of the Scheme Major Changes for 2014 Partner Organisations. Hints for practice Kl HapMap. Peter Castaldi. January 29, 2013. Objectives. Introduce the concept of linkage disequilibrium (LD). Describe how the . HapMap. project provides publically available information on genetic variation and LD structure. Prepared by -. RAKESH CHOUDHARY. M.Sc.(AGRI) . GENETICS AND PLANT BREEDING . . WELCOME. Linkage and Chromosome. Mapping . Linkage and Chromosome. Mapping . Genetic linkage was first discovered by the . ?. 1. 24 June, 2015 (ICSD). E-mail: minaba@lynx.let.hokudai.ac.jp. Misato Inaba. Nobuyuki Takahashi. *1 JSPS Research . Fellow, . Japan. *2 Hokkaido University, Japan. 1. . 2. 2. Overview. As the solution to . Key Reference. Li, Q., and R. L. Wu, 2009 A . multilocus. model for constructing a linkage disequilibrium map in human populations. . Statistical Applications in Genetics and Molecular Biology . 8 (1): Article 18.. Connecting system components. Allows configuring automatic actions. Triggering outputs based on specific inputs. Used for removing human reliance. Also used as backup to normal operations. Basic concepts. Recombination. Missouri University of Science and Technology. Recombination explores the search space. Classic Recombination. N-point crossover. Uniform. Limitation. Disrupting good partial solutions via crossover is problematic. A) Alleles at different loci are independent. B) Alleles at different loci are physically close to each other and on the same chromosome. C) Alternate alleles at the same locus are not independent. D) Alleles at different loci are not independent. Key Reference. Li, Q., and R. L. Wu, 2009 A . multilocus. model for constructing a linkage disequilibrium map in human populations. . Statistical Applications in Genetics and Molecular Biology . 8 (1): Article 18.. Chromosome mapping by recombination . Meiosis is the basis of transmission genetics. The recombination that occurs during meiosis (in heterozygotes) generates data that are a useful tool for making linkage maps. 2015 . – Session . 2 . 2015 Rule changes, Partner contributions & General BUDGET information. Deakin. Research – Grants. Rose Firkin - Executive Officer – Grants. Dr Tracey McInerney – Senior Grants Officer. Motor Vehicle Injury Data Linkage Challenges. Jennifer Mathieu, PhD, Mike Fulk, Aileen Prior, Liz Richerson, Keith Miller, PhD; MITRE. Erica Spies, PhD; Centers for Disease Control and Prevention (CDC). Systematic Reviews: Hints and tips www.ccace.ed.ac.uk Ellen Backhouse www.ccace.ed.ac.uk Our systematic review Early life risk factors for stroke and subclinical cerebrovascular disease Figure 1. PRISMA Flow chart of methodology and study selection Paul A. Smith, S3RI, University of Southampton. Shelley Gammon, Sarah Cummins, Christos Chatzoglou, Office for National Statistics. Dick . Heasman. 1. Outline. Record linkage and strategies. Quality measures for record linkage.