PPT-Congenital and Acquired Hemolytic Anemias

Ellis J Neufeld MD PhD Disclosure Information Ellis J Neufeld MD PhD Research Funding Agios Pharmaceuticals Advisory Board Agios Pharmaceuticals Hemolytic Anemia Increased destruction . MANAGEMENT OF NYSTAGMUS. From. Dr.Shashank. . Ranade. DNB, DO, DOMS,FCPS,FICO(UK). Fellow, Pediatric Ophthalmology, Strabismus & Ocular motility disorders . [International Guest Speaker, UK]. Anemia:. Deficiency of hemoglobin in the blood.. Causes: . Too few RBCs.. Too little hemoglobin in cells. Decreased packed cell volume.. This may be due to. :. decreased production of RBCs.. increased destruction.. Shejal Patel DO. Case 1. Mr. X is a 60 year old male with no past medical history and comes into the ER with complaints of fatigue and shortness of breath x 5 days. He takes no medications. He is noted on exam to be jaundiced and . RBCs destroyed. prematurely.. Arrows. . indicate cells. being destroyed; . Acquired (. thru . ertain. chemicals. or bacteria/viruses) . o. r . inherited.. Symptom of o. ther disorders.. Sofi. MD; FRCP (London); . FRCEdin. ; . FRCSEdin. Hemolytic anemia. is a form of anemia due to . hemolysis. , the abnormal breakdown of red blood cells (RBCs), either in the blood vessels (intravascular) or elsewhere in the human body (. Ali Al Khader, M.D.. Faculty of Medicine. Al-Balqa’ Applied University. Email: ali.alkhader@bau.edu.jo. Sickle Cell Anemia. The . most common familial hemolytic . anemia in . the . world. Sickle . cell . Michael R. Jeng, MD. Michael R. Jeng, MD. NO FINANCIAL DISCLOSURES. 1. Red blood cell biology. 2. Hemolytic anemia: definition, assessment. 3. Approach to diagnosis. 4. . Microangiopathic. hemolytic anemias. 19. Learning Objectives—Level I. At the end of this unit of study, the student should be able to:. List the antibody systems or specificities usually involved in:. cold agglutinin syndrome. paroxysmal cold hemoglobinuria (PCH). Definition. . Nystagmus. is an involuntary rhythmic shaking or wobbling of the eyes. The term . nystagmus. is derived from the Greek word ‘. nystagmos. ’ which was used to describe the wobbly head movements of a sleepy individual. . How to classify . anemias. on the basis. of etiology and RBC parameters:. 1.) Decreased production vs. RBC loss (increased destruction or bleeding). 2.) RBC Size:. Macrocytic . ,. microcytic , normocytic. Persistent . hyperplastic. primary vitreous. . PHPV is a congenital condition caused by failure of the normal regression of the primary vitreous. It is usually associated with unilateral vision loss. Sendi P, Johansson L, Dahesh S, Van Sorge NM, Darenberg J, Norgren M, et al. Bacterial Phenotype Variants in Group B Streptococcal Toxic Shock Syndrome. Emerg Infect Dis. 2009;15(2):223-232. https://doi.org/10.3201/eid1502.080990. S. Al-. Qahtani. ASSOCIATE PROFESSOR. CONSULTANT . HAEMATOLOGIST . DEPARTMENT OF PATHOLOGY. LEARNING OBJECTIVES. To be able to define haemolysis and hemolytic anemia.. To be able to classify hemolytic anemias into congenital and acquired types, and to know the etiological factors in each division.. DR AMRITA KURIAN. JUNIOR RESIDENT. INTRODUCTION . Hemolytic anemia – classification : . Inherited / Acquired. Acute / Chronic. Intravascular / Extravascular. Intracorpuscular. / . Extracorpuscular.