PPT-HEMOLYTIC ANEMIA Dr. M. A

Sofi MD FRCP London FRCEdin FRCSEdin Hemolytic anemia is a form of anemia due to hemolysis the abnormal breakdown of red blood cells RBCs either in the blood vessels intravascular or elsewhere in the human body . Fahd . Alareashi. .. . Anemia…. What is Anemia?. A condition characterized by a decrease in RBCs mass, hemoglobin or RBCs count.. Adult male: . Hb. .  13 g/. dL. , or . Hct. .: 41%.. Adult Females: . Deficiency. (G6PDD). The . glycolytic. pathway . is the main source of energy (ATP). The . hexose. monophosphate ‘shunt’ pathway. . provides the main source of reduced . nicotinamide. adenine . An interesting phenomenon of rare numbers. .. Meghan E. Kapp, MD MS. 30 June 2014. Hemolytic Anemia. Red Blood Cells are destroyed and removed from the bloodstream before their normal lifespan is over. MethodsIn vitrofrom jellyfish CatostylustagiRita Soeiro1andZilda Morais11Centro de Investigao Interdisciplinar Egas Moniz CiiEM Campus Universitrio Quinta da Granja 2829-511 Caparica PortugalCnidarian red blood cell mass . or . blood hemoglobin concentration. . In practice, anemia most commonly is defined by reductions in one or both of the following:. Hematocrit (HCT) – The HCT is the fractional volume of a whole blood sample occupied by RBCs, expressed as a percentage. As an example, the normal HCT in a child age 6 to 12 years is approximately 40 percent.. a sign . of an underlying . disorder. There are several kinds of anemia. . A. . physiologic . approach classifies anemia according to whether. the deficiency in erythrocytes is caused by a defect in . referance. range for the age and sex. The normal ranges vary with age . -neonate < 14g/dl. -1-12mths < 10mg/dl. -1-12y< 11 g/dl. Causes of anemia can be from. Reduced cell production. Increased destruction. a pathophysiological condition in which the body cannot meet its demands for oxygen. . M: . Hb. <13.5 . Hct. <41 . F. : . Hb. <12 . Hct. <36 . Erythrocyte Indices . Hgb. M: 14.0-18.0 . Michael R. Jeng, MD. Michael R. Jeng, MD. NO FINANCIAL DISCLOSURES. 1. Red blood cell biology. 2. Hemolytic anemia: definition, assessment. 3. Approach to diagnosis. 4. . Microangiopathic. hemolytic anemias. .. Epidemiology.. Classification.. Review the terminology used to discuss anemia.. Evaluation:. .. . • Address clues in the history and exam that can direct the evaluation. . • Describe one approach to using lab tests to make the diagnosis. . What is anemia. What are symptoms and signs of anemia. What is classification and different types of anemia. What are causes of different types of anemia. Learning Objectives. Anaemia. Significant reduction . Sendi P, Johansson L, Dahesh S, Van Sorge NM, Darenberg J, Norgren M, et al. Bacterial Phenotype Variants in Group B Streptococcal Toxic Shock Syndrome. Emerg Infect Dis. 2009;15(2):223-232. https://doi.org/10.3201/eid1502.080990. S. Al-. Qahtani. ASSOCIATE PROFESSOR. CONSULTANT . HAEMATOLOGIST . DEPARTMENT OF PATHOLOGY. LEARNING OBJECTIVES. To be able to define haemolysis and hemolytic anemia.. To be able to classify hemolytic anemias into congenital and acquired types, and to know the etiological factors in each division.. DR AMRITA KURIAN. JUNIOR RESIDENT. INTRODUCTION . Hemolytic anemia – classification : . Inherited / Acquired. Acute / Chronic. Intravascular / Extravascular. Intracorpuscular. / . Extracorpuscular.