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Definitions: Seizure, Epilepsy, Epilepsy Syndrome Definitions: Seizure, Epilepsy, Epilepsy Syndrome

Definitions: Seizure, Epilepsy, Epilepsy Syndrome - PowerPoint Presentation

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Uploaded On 2020-01-19

Definitions: Seizure, Epilepsy, Epilepsy Syndrome - PPT Presentation

Definitions Seizure Epilepsy Epilepsy Syndrome Goals of Medical Therapy Individualizing AED Selection Comorbidities AED Mechanisms of Action Effectiveness of AED Combination Therapy Based on Mechanism of Action ID: 773268

cont perampanel ezogabine clobazam perampanel cont clobazam ezogabine eslicarbazepine effects adverse efficacy dosing clinical pharmacokinetics moa indication references aed

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Presentation Transcript

Definitions: Seizure, Epilepsy, Epilepsy Syndrome

Goals of Medical Therapy

Individualizing AED Selection

Comorbidities

AED Mechanisms of Action

Effectiveness of AED Combination Therapy Based on Mechanism of Action

Effectiveness of AED Combination Therapy Based on Mechanism of Action (cont)

Newest AEDs for Partial-Onset Seizures

Clobazam: Indication

Clobazam: MOA and Pharmacokinetics

Clobazam: Clinical Efficacy

Clobazam: Adverse Effects

Clobazam: Drug Interactions

Clobazam: Summary/Dosing

Eslicarbazepine Acetate: Indication/ MOA

Eslicarbazepine: Pharmacokinetics

Eslicarbazepine: Clinical Efficacy

Eslicarbazepine: Efficacy (cont)

Eslicarbazepine: Adverse Effects

Eslicarbazepine: Drug Interactions/Dosing

Ezogabine: Indication/MOA

Ezogabine: Pharmacokinetics

Ezogabine: Clinical Efficacy

Ezogabine: Adverse Effects

Ezogabine: Adverse Effects (cont)

Ezogabine: Dosing

Perampanel: Indication/MOA

Perampanel: Pharmacokinetics

Perampanel: Clinical Efficacy

Perampanel: Pooled Analysis of 3 Phase 3 Studies

Perampanel: Adverse Effects

Perampanel: Drug Interactions

Perampanel: Dosing

Perampanel: Dosing (cont)

Abbreviations

Abbreviations (cont)

References

References (cont)

References (cont)

References (cont)