PPT-What's New in Atopic Dermatitis

Changing Landscape of Therapeutic Options Burden of AD in Adults Dupilumab Phase 3 Trials Study Design Dupilumab Phase 3 Trials Primary Efficacy Data Dupilumab Phase 3 Trials Secondary Efficacy Data. The Allergist's Approach. Thomas A. Lupoli, D.O.. Board Certified Allergist/Immunologist. Background & Disclosures/Conflicts. Allergy & Asthma Specialists of North Florida. Florida Allergy, Asthma & Immunology Society. This program will include a discussion of off-label treatment and investigational agents not approved by the FDA for use in the US, and data that were presented in abstract form. These data should be considered preliminary until published in . Case Scenario #1 Luis is a 9-year-old male seen in clinic with a complaint of worsening pruritus causing difficulties in school and sleep. History: He first complained of dry, itchy skin on the flexural areas of his arms and legs about 2 years ago. Symptoms are worse in winter. Module Overview In this module, we discuss key pathophysiologic mechanisms of atopic dermatitis, such as barrier dysfunction, bacterial over-colonization, and immune dysregulation. We’ll also highlight some of the pathophysiologic mechanisms that serve as treatment targets. Pediatric Continuity Clinic Curriculum. Created by: Matthew Pertzborn, PGL-2. Objectives. Describe the common clinical presentation and diagnosis of atopic dermatitis. Understand the management of atopic dermatitis. First targeted biologic for adults with moderate-to-severe atopic dermatitisRapid and sustained improvement in Lesion extent and severity Quality-of-life measuresDiscontinuation rates due to adverse e pl Dermatitides Inflammation of the skin The term eczema also refers to an inflammation of the skin The term eczema is often colloquially used to define the disease atopic dermatitis Descriptive ter Program Overview. Atopic Dermatitis: An Overview and Key Challenges. Atopic Dermatitis: Characteristics. Epidemiology of Atopic Dermatitis. EASI, SCORAD, and IGA Scales to Grade . Atopic Dermatitis. The Complex Pathophysiology of . Lawrence A. Schachner, M.D. Professor, Chair Emeritus and . Stiefel. Laboratories Chair. Director of the Division of Pediatric Dermatology . Department of Dermatology & Cutaneous Surgery . Professor, Department of Pediatrics. appropriately manage their patients. Cutis. 2006;78:241-247. )NCIDENCE�AND�0REcAbENCE Recent population-based studies from Washington state have estimated that 17.2% of the US populati 119 is a common and frequently familial inflammatory dermatosis, which usually appears during infancy or early childhood and is often associated with other atopic diseases such as asthma, allergic rh Abdullah ALAKEEL, MD. Assistant Professor. Consultant Dermatologist. Department of Dermatology- KSU. Eczema. Definition: inflammation of the skin. Eczema vs. dermatitis. Acute eczema: . erosion, oozing and vesicles . Pruritus. . is. . most. . common. . symptom. , . along. . with. . erythematous. , . scaly. . lesions. Definition:. Chronic, pruritic, inflammatory skin disease that occurs most frequently in children but also affects adults. Ointment,. a Novel, Nonsteroidal Phosphodiesterase 4 (PDE4) Inhibitor for the Topical Treatment of Atopic Dermatitis (AD) in Children and Adults. Paller. A, . Wynnis. T, . Lebwohl. M, et al.. http://www.jaad.org/article/S0190-9622(16)30330-9/abstract.