PPT-AMYLOIDOSIS Definition: A condition in which normally soluble proteins become insoluble

These insoluble proteins misfolded proteins are called amyloid More than 20 different proteins can aggregate to form the amyloid Amyloid is composed of nonbranching fibrils. Determine if the following are soluble or insoluble using the solubility table: . CaSO. 4. Ni. 3. (PO. 4. ). 2. KOH. HgCl. . MgCrO. 4 . Solubility Table: . ( don’t copy…already on your salmon sheet). Year 11. CONTENTS. Acidity and alkalinity. Indicators. pH. Acids. General methods for making salts. Making salts from metal oxides. Making salts from metal carbonates. Making salts from metals. Lipids-I. -Lipids are esters of long chain fatty acids and alcohols.. -. Fatty acids are lipids’ building blocks . -It can be defined as nonpolar organic compound insoluble in polar solvent , but soluble in organic solvents such as benzene ,ether, chloroform and boiling alcohol.. Grade 10. Acids. Sour. Turn litmus red. pH less than 7. Dissolve carbonate rocks. Corrode metals . Conduct electricity. Acids. Acids are substances that give H. +. ions when added to water.. Alkalis. What are we testing to find?. Precipitate tests are used to detect the presence of an ion within a solution.. Precipitate tests may test for positive ions, for example magnesium ions (Mg. 2+. ). . Positive ions are called . Focus on equations with a precipitate.. Total Ionic Equations. Write the equation . (synthesis, decomposition, etc. .). check . for reactants and products that are . soluble. or . insoluble. .. We usually assume the reaction is in . DR.MAYSEM . LEC.4. Rejection of Tissue Transplants:. -Allografts. . transplantation of organs from one individual . to. . another . of the same species..  . . Rejection. is a complex phenomenon involving both cell- and antibody-mediated reactions that destroy the graft.. A. –Eyesight (r/o/y F&V). D. – Bones (sunlight, milk). E. – cell membranes . K . – blood CLOTTING . C. – Immune system, collagen, wounds (citrus, broccoli). B-complex. Folate. –neural tube (whole grains, dark green veggies, nuts): *. A Spotlight on New Disease-Modifying . Therapies Across the Clinical Spectrum. Supported by an educational grant from Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC.. About These Slides. . Razick. overview. Patient presentation. CC: . “I feel good”. AF is an 88-year-old female returning to the Advanced Heart Failure Clinic for a follow up appointment where she is monitored closely for her heart failure associated with a PYP scan for possible amyloidosis. . Ibraheem. Amyloidosis . is a disorder characterized by the extracellular deposits of . misfolded. . proteins that aggregate to form insoluble fibrils (beta-pleated sheet) conformation.. Generally . Fresh & Dried Fruits Serving Soluble Fiber (g) Insoluble Fiber (g) Total Fiber (g ) Apple with skin 1 medium 4.2 1.5 5.7 Apricots, dried 4 medium 1.8 1.7 3.5 Banana 1 medium 2.1 0.7 2.8 Blackberrie Anita D’Souza, MD, MS. Froedtert. & MCW Cancer Center. Milwaukee, WI. Objectives. Types of amyloidosis. How does amyloidosis form?. Why does myeloma sometimes make amyloid?. Treatment of amyloidosis. Shifting Treatment Paradigm. Jeffrey A. Zonder, MD. Professor of Oncology, Wayne State University. Leader, Multiple Myeloma & Amyloidosis MDT. Co-Leader, Molecular Therapeutics Program. Karmanos.