PPT-Advances in the Treatment of Iron Deficiency Anemia and Related Disorders in CKD

Program Goals Hepcidin in Chronic Kidney Disease Treatment of Iron Deficiency Anemia Assessment of IV Iron in Patients With NonDialysisDependent CKD DOPPS Study Ferric Pyrophosphate Phosphate Binders.   . Seventh International Symposium in Continuing Nursing Education/March, 2014. 3/2014. Donald W. McLaren, MD. Objectives. To discuss how to evaluate and determine cause of anemia. To discuss Iron deficiency (ID) and Iron Deficiency Anemia (IDA) - causes, evaluation, signs, symptoms, treatment and prevention at different ages. Rafi Ahmed, MD. Hematology and Oncology Fellow. 4-10-14. Overview. Not a diagnosis, but a sign of disease. Warrants an investigation. Definition: Reduction in oxygen carrying capacity of blood due to decreased erythrocyte mass. Assistant Professor of Medicine & Oncology, Division of Hematology. Disclosures. None. Objectives. Understand the basic physiology of iron absorption, transport and storage. Understand the causes of iron deficiency and the compensatory responses seen in clinical lab tests. IRON OVERLOAD. IRON. 10-15 mg/day in diet; 5-10% absorbed. Absorption increased in iron deficiency, pregnancy, erythroid hyperplasia, hypoxia. Heme iron absorbed best. Fe. 2 . much better than Fe. 3 . Hematology and Oncology Fellow. 4-10-14. Overview. Not a diagnosis, but a sign of disease. Warrants an investigation. Definition: Reduction in oxygen carrying capacity of blood due to decreased erythrocyte mass. “Anemia”. . Dr. Sabin Thomas, M. Pharm. Ph. D.. Assistant . Professor. in . Pharmacy. Practice. School. of . Pharmacy. , CPN. University. of Nizwa. University of Nizwa. College of Pharmacy and Nursing. red blood cell mass . or . blood hemoglobin concentration. . In practice, anemia most commonly is defined by reductions in one or both of the following:. Hematocrit (HCT) – The HCT is the fractional volume of a whole blood sample occupied by RBCs, expressed as a percentage. As an example, the normal HCT in a child age 6 to 12 years is approximately 40 percent.. By Dr. Zahoor. 1. Anemia. What is Anemia?. . Anemia is present when there is decrease in hemoglobin (Hb) in the blood below the reference level for the age and sex . 2. 3. Normal Values for Peripheral Blood. .. Epidemiology.. Classification.. Review the terminology used to discuss anemia.. Evaluation:. .. . • Address clues in the history and exam that can direct the evaluation. . • Describe one approach to using lab tests to make the diagnosis. . Anemia . Rand . Al-shayeb. Step up to medicine. Davidson's Principles and Practice of Medicine. Diagnosing the cause of anemia. If . microcytic anemia (MCV<80), the differential diagnosis includes the following. DR. SANJANA BHAGWAT. MODERATOR : DR. A. . GANAPULE. Normal iron metabolism. IRON METABOLISM. Genetic forms of iron deficiency . anaemia. Mutations in genes encoding :. DMT-1. Glutaredoxin. 5. Transferrin. Lec. . Dr. Abeer Abdulhadi Rashid. Introduction. . . Anemia. is . a reduction in the concentration of hemoglobin (. Hgb. ) that results in reduced oxygen. c. arrying. capacity of the blood. . Some patients with anemia may be asymptomatic initially, but eventually, the lack of oxygen to tissues results in fatigue, lethargy, shortness of breath, headache, edema, and tachycardia. . Department of internal medicine 1. with course of cardio-vascular pathology. Complete blood count (CBC). RED BLOOD CELL COUNT. M – 4,5-5,5 *10. 12. ; F – 3,5-4,5 *10. 12. . HEMOGLOBIN. M – 130-160 g/l (13-16 mg/dl); . Objectives. Learn about iron deficiency anemia. Learn about . anemia . of chronic disease. Distinguish between iron deficiency anemia and anemia of chronic disease . .