PPT-Cholinergic transmission(Part-II)

Dr Rashmi Rekha Kumari Asstt Prof Deptt Of Pharmacology amp ToxicologyBVCPatna14 Muscarinic and Nicotinic Action of Ach Dale distinguished two type of effect during a study of pharmacological action of Acetylcholine in cat. Balanced and unbalanced transmission line Transit time effect on a transmission line at high frequencies Dominance of the reactive component over resistive component Concept of distributed elements and conditions under which the lumped element circu . Kshitij Desai, . Mayuresh. . Randive. , . Animesh. . Nandanwar. . . Basic Design. Sensor Network Architecture. Internet. Sensor Network. Sink. Architecture of a Sensor Node. Ref: Energy Conservation in Wireless Sensor Networks – a Survey. A Selective Overview. Carl Rosow, M.D., Ph.D.. Disclosures. Consultant – Salix Pharmaceuticals. Topics for Today. Pharmacodynamics. Receptors, potency, efficacy. Agonists, antagonists. The dose response curve. A:- Precursor -. Choline. B :- Enzyme- . . Synthesizing - Choline . Acetylase. . Degrading - . A. cetycholine. Esterase . (TRUE). . - . Cholinergic Agonists Direct-Acting Cholinomimetics Direct-Acting Cholinergic Agonists (N & M) Cholinergic agonists (parasympathomimetics) mimic the effects of ACh on cholinoceptors. These agents broadly classified into A:- Precursor -. Choline. B :- Enzyme- . . Synthesizing - Choline . Acetylase. . Degrading - . A. cetycholine. Esterase . (TRUE). . - . Cholinergic antagonist is a general term for agents that bind . to . cholinoceptors. (muscarinic . or nicotinic) and prevent the . effects . Abd. Al- Kader. PhD Pharmacology. THE CHOLINERGIC . NEURON. 1. The . preganglionic. fibers terminating in the . adrenal medulla. 2. The autonomic ganglia . (both parasympathetic and sympathetic. ). Dr.. . Nirbhay. Kumar. Asstt. . Professor & Head. Deptt. . of Veterinary Pharmacology & Toxicology. Bihar Veterinary College, Bihar Animal Sciences University, Patna. Cholinergic Transmission. that bind . to . cholinoceptors. (. muscarinic. . or nicotinic) . and prevent . the effects of . acetylcholine (. ACh. ) and . other . cholinergic agonists. The most clinically. useful of these agents are selective . . Dr.. Rashmi . Rekha. Kumari. Asstt. . Prof, . Deptt. . Of Pharmacology & Toxicology,BVC,Patna-14. Cholinergic transmission. Neurohumoral. transmission . either at synapse or neuroeffector junction in which acetylcholine act as a humoral agent(neurotransmitter) for transmission of action potential across the junction. Direct-Acting Cholinergic Agonists (N & M). Cholinergic agonists (parasympathomimetics) mimic the effects of ACh on cholinoceptors.. These agents broadly classified into. :. Endogenous choline esters, Ach. muscarinic. antagonist / . muscarinic. blocker.. OBJECTIVES. Classify & describe cholinergic antagonists. Explain actions, therapeutic uses & adverse reactions of cholinergic antagonists. Cholinergic antagonist / Cholinergic blockers. Written by Dr Amy Armstrong Nov 2023 . Emergency Medicine Teaching Programme. Clinical Case. A 45-year-old farmer is brought in as a standby to resus, having been found unwell in an agricultural store on his farm by another worker. .