PPT-Cholinergic Agonists 1 Dr. Dalia

Abd Al Kader PhD Pharmacology THE CHOLINERGIC NEURON 1 The preganglionic fibers terminating in the adrenal medulla 2 The autonomic ganglia both parasympathetic and sympathetic . Teaser. Zak Fallows. 2013-07-03. http://datb.mit.edu. pharmacology@mit.edu. 1. How the Brain Works. You have about 100 billion brain cells, which are called neurons.. Each neuron has about 1,000 connections, called synapses. (This number is extremely variable.). Muscarinic Agonists and Antagonists. Cholinergic Drugs. Agents that influence the activity of cholinergic receptors. Most mimic or block the actions of acetylcholine.. Cholinesterase inhibitors . Indirectly prevent the breakdown of acetylcholine. A Selective Overview. Carl Rosow, M.D., Ph.D.. Disclosures. Consultant – Salix Pharmaceuticals. Topics for Today. Pharmacodynamics. Receptors, potency, efficacy. Agonists, antagonists. The dose response curve. Pharmacology 49.222. Bill Diehl-Jones RN, PhD. Faculty of Nursing and Department of Zoology. Agenda. A Zen Review. Overview of CNS and ANS. Neurotransmitters and 2. nd. Messengers. Cholinergic Agonists and Antagonists. ) effects on CB1 Inverse Agonists. Erin Cochran. Endocannabinoid System. Pharmacology Terms. Basal. or . Constitutive. . activity-. . physiological response . in . the absence of an agonist or inverse . Cholinergic Agonists Direct-Acting Cholinomimetics Direct-Acting Cholinergic Agonists (N & M) Cholinergic agonists (parasympathomimetics) mimic the effects of ACh on cholinoceptors. These agents broadly classified into A:- Precursor -. Choline. B :- Enzyme- . . Synthesizing - Choline . Acetylase. . Degrading - . A. cetycholine. Esterase . (TRUE). . - . Nervous System. Part 2. . Thomas E. Tenner, Jr., Ph.D.. Dept. of Medical Education. Dept. Pharmacology & Neuroscience. tom.tenner@ttuhsc.edu. 743-7169. 1. Recommended Background Reading :.  . Chapters 7, 8, 9, and 10 . Dr.. . Nirbhay. Kumar. Asstt. . Professor & Head. Deptt. . of Veterinary Pharmacology & Toxicology. Bihar Veterinary College, Bihar Animal Sciences University, Patna. Cholinergic Transmission. Cancer Patients. Dalia A. . Hamdy. PhD, . RPh. , MRSC. Assistant Professor . Faculty of Pharmacy. Alexandria University. dr.daliahamdy@gmail.com. 3. rd. November 2015. Outline. Introduction to . Azole antifungals in . that bind . to . cholinoceptors. (. muscarinic. . or nicotinic) . and prevent . the effects of . acetylcholine (. ACh. ) and . other . cholinergic agonists. The most clinically. useful of these agents are selective . . Dr.. Rashmi . Rekha. Kumari. Asstt. . Prof, . Deptt. . Of Pharmacology & Toxicology,BVC,Patna-14. Cholinergic transmission. Neurohumoral. transmission . either at synapse or neuroeffector junction in which acetylcholine act as a humoral agent(neurotransmitter) for transmission of action potential across the junction. Direct-Acting Cholinergic Agonists (N & M). Cholinergic agonists (parasympathomimetics) mimic the effects of ACh on cholinoceptors.. These agents broadly classified into. :. Endogenous choline esters, Ach. muscarinic. antagonist / . muscarinic. blocker.. OBJECTIVES. Classify & describe cholinergic antagonists. Explain actions, therapeutic uses & adverse reactions of cholinergic antagonists. Cholinergic antagonist / Cholinergic blockers.