PPT-Cholinergic drugs Are drugs act on receptors that are activated by acetylcholine(ACH)

ACH is synthesized in the cholinergic neurons from choline and acetyl CoA then stored in synaptic vesicles then it will be release into synaptic gap to bind post synaptic receptors and lead to biological response. Muscarinic Agonists and Antagonists. Cholinergic Drugs. Agents that influence the activity of cholinergic receptors. Most mimic or block the actions of acetylcholine.. Cholinesterase inhibitors . Indirectly prevent the breakdown of acetylcholine. Major Psychiatric Disorders . Psychoses. eg schizophrenia. Affective disorders. . eg depression and mania. Psychoses . False perceptions (Hallucinations). False beliefs (Delusions). Affective Disorders . Define cholinergic Drugs ?. Cholinergic Drug are agent which produce the action similar to those seen by the stimulation of parasympathetic nervous system.. 2) Write the enzyme responsible for metabolism of acetylcholine . A Selective Overview. Carl Rosow, M.D., Ph.D.. Disclosures. Consultant – Salix Pharmaceuticals. Topics for Today. Pharmacodynamics. Receptors, potency, efficacy. Agonists, antagonists. The dose response curve. Define cholinergic Drugs ?. Cholinergic Drug are agent which produce the action similar to those seen by the stimulation of parasympathetic nervous system.. 2) Write the enzyme responsible for metabolism of acetylcholine . SYSTEM. . . TWO MAJOR DIVISIONS. PARASYMPATHETIC. -ganglia close to organ innervated. -. preganglionic. fibers are . myelinated. and long. -postganglionic fibers short and . unmyelinated. SYMPATHETIC. Chapter 14 Drugs Affecting The Nervous System The nervous system controls, directs and coordinates bodily functions 2 main divisions of the nervous system: Central Nervous System (CNS) - brain and spinal cord Week 1. By Renee . McCroskey. BSN, RN. Pharmacology Fundamentals. Chapters 1-4. Things to think about…. What . drug is ordered. Name (generic and trade) and drug classification. Mechanism of action. 11/10/17 . Case 1: . 18 month old girl brought the ER by ambulance after grandmother was unable to wake her up from a long nap. . No concurrent illness. On exam: Shallow breathing, moans and withdraws in response to pain, does not open her eyes. Rest of physical exam is normal. . Abd. Al- Kader. PhD Pharmacology. THE CHOLINERGIC . NEURON. 1. The . preganglionic. fibers terminating in the . adrenal medulla. 2. The autonomic ganglia . (both parasympathetic and sympathetic. ). Dr.. . Nirbhay. Kumar. Asstt. . Professor & Head. Deptt. . of Veterinary Pharmacology & Toxicology. Bihar Veterinary College, Bihar Animal Sciences University, Patna. Cholinergic Transmission. that bind . to . cholinoceptors. (. muscarinic. . or nicotinic) . and prevent . the effects of . acetylcholine (. ACh. ) and . other . cholinergic agonists. The most clinically. useful of these agents are selective . Professor. Dr Ahmed Abu . Raghif. Ph.D. . Pharmacology. Complex Organ Control: The Eye. The pupil is under reciprocal control by the SANS (via receptors on the . pupillary. dilator muscle) and the PANS (via . Objectives:. . List the classification of antipsychotic drugs used in schizophrenia.. Describe briefly the mechanism of antipsychotic action of these drugs. . Describe the pharmacological actions of antipsychotic drugs. .