PPT-Cold-Stored Platelets and the Impact on Blood

ColdStored Platelets and the Impact on Blood Center Operations James R Stubbs MD Chair Transfusion Medicine Mayo Clinic Rochester Minnesota Disclosures None Presentation Outline Mayo Clinic Donor Services Who we are Mayo Clinic. Blood . is the body’s only fluid tissue. It is composed of liquid plasma and formed elements. Formed elements include: . Erythrocytes, or red blood cells (RBCs). Leukocytes, or white blood cells (WBCs). “Blood transfusion is like marriage: it should not be entered upon lightly, unadvisedly or wantonly or more often than is absolutely necessary. .” . . –Robert Beal, past director of International Federation of Red Cross. “River of life”. Transports everything that must be carried from one place to another within the body:. Nutrients. Wastes. Heat. Composition of Blood. Blood cells or formed elements:. Red blood cells – transports oxygen. Waterford, WI. A wound occurs when the a break in tissue occurs. . This can be because of trauma.. It can also be intentional, such as is the case during a surgery.. There are . five kinds . of . wounds (PAAIL).. Elizabeth S. Allen, MD. Outline. Platelets. Problems with Platelets. Pathogen Reduced Platelets. UCSD Implementation Strategy. Objectives. Understand the risks of conventional platelet transfusion. Describe the mechanism and effects of pathogen reduction technology. SEO is anything but a “one size fits all” strategy. What works for one website may not work for another. And what worked for you in the past may not yield the same results in the future. If your cold emails do not match these standards then yes, you’ve got to go back and revise them. Yes, that’s a pain, but at least you’ll know what to do the next time around. INTERCEPT ® Blood System for Platelets Pathogen Reduction System (Psoralen/UVA Treatment) Nursing Training Module MKT-EN 00422-08 v1.0 When you think of the risks associated with blood product transfusions, what : the smallest of the formed elements in blood, a disk-shaped, non-nucleated blood element with a fragile membrane, formed in the red bone marrow by fragmentation of . megakaryocytes. . Platelets tend to adhere to uneven or damaged surfaces, and there are an average of about 250,000 per mm. blood is collected as whole blood, as shown below:. Blood can be stored as whole blood (with all of the plasma present) or, much more commonly, as packed red blood cells (PRBC's) in which about 70% of the plasma has been removed.. Practical Hematology Lab. - LAB . -. Platelet . Satellitism. Morphology. Platelets clumped around neutrophils. .. Found . in. EDTA in vitro induced change of no clinical significance except false low platelet count (in vitro).. .” . . –Robert Beal, past director of International Federation of Red Cross. Transfusions: History. 1660s: First experiments in blood transfusion, transfused dog blood to humans. Patient died and experiments were banned.. By . Dr. Sunita Mittal. Learning Objectives. Platelets Morphology. Hemostasis. Primary hemostasis. Platelet plug formation. Disorders of . p. rimary hemostasis. Secondary hemostasis. Disorders of secondary hemostasis. Platelets are the smallest formed elements in the blood, normally ranging in size from 2-4 microns. . Platelets function in the coagulation of blood.. A normal platelet count is 150,000-400,000/c.mm.in human .