PPT-Platelet Counts Platelets:

Platelets are the smallest formed elements in the blood normally ranging in size from 24 microns Platelets function in the coagulation of blood A normal platelet count is 150000400000cmmin human . Platelets aggregation. Studying Platelets Disorders. . Numbers. . CBC. PLT count. PLT morphology. Function. . Bleeding . Time (BT). Platelet Aggregation. Whole blood aggregation . Platelet-rich plasma aggregation. Thrombocytes. Platelets (Thrombocytes). 2- 4 micromillimeters in diameter. 250,000 – 400,000 per microliter . (too few thrombocytopenia – too many thrombocytosis). Lifespan on average 6 – 10 days. Joanna Rupa-Matysek. Hemostatic. System - . general. . information. Normal . hemostatic. system . vessel wall. circulating blood platelets. blood coagulation and . fibrynolysis. Bleeding. . Diathesis. Platelets aggregation. Studying Platelets Disorders. . Numbers. . CBC. PLT count. PLT morphology. Function. . Bleeding . Time (BT). Platelet Aggregation. Whole blood aggregation . Platelet-rich plasma aggregation. Thrombocytes. Platelets (Thrombocytes). 2- 4 micromillimeters in diameter. 250,000 – 400,000 per microliter . (too few thrombocytopenia – too many thrombocytosis). Lifespan on average 6 – 10 days. purpura. (ITP). Immune thrombocytopenia . purpura. (ITP). 1- Chronic ITP: . This is relatively common disorder ,with highest incidence in . women. . 15-50 y. ,it is commonest cause of thrombocytopenia without anemia or neutropenia ,it is usually . REPORT DOCUMENTATION PAGE A D-A202 503 ,b. RESTRICTIVE MARKINGS -I HULE COP! -- 3. DISrRAUrlON/AVAILABeLiTY OF REPORT Approved for public release; 2b, DECLASSIFICArION/DOWNGF(ADING SCHEDULE distributi thrombocytopenia. ) constitutes an important cause of generalized bleeding.. A count less than 100,000 platelets/. μL. is generally considered to constitute thrombocytopenia. . Platelet counts in the range of 20,000 to 50,000 platelets/. Mohammad Faranoush,MD . Professor of pediatric Hematology Oncology. Iran University of Medical Sciences. Rasool Akram Medical Complex. Disclosures. No conflict of interest. Introduction. Platelets play a crucial role in hemostasis.. At the end of this unit of study, the student should be able to:. Describe the normal morphology and number of platelets on a peripheral blood smear and state the normal life span and concentration of platelets in the blood.. a a a T I P Idiopathic Thrombocytopenic Purpura Ishfaq. . Bukhari. Dec. 2012. In healthy vasculature, circulating platelets are maintained in an inactive state by nitric oxide (NO) and . prostacyclinre. (PGI2)leased by endothelial cells lining the blood vessels.. . Platelet products, . volume . and expected . p. latelet . i. ncrement . Indications for platelet transfusions . Decision to transfuse should be based on both laboratory investigations and assessment of the clinical condition with careful consideration of risks & benefits. . By . Dr. Sunita Mittal. Learning Objectives. Platelets Morphology. Hemostasis. Primary hemostasis. Platelet plug formation. Disorders of . p. rimary hemostasis. Secondary hemostasis. Disorders of secondary hemostasis.