And why was his work so important Gregor Mendel Gregor Mendel was a monk who lived in the 1800s Mendels Mind Wandered Mendel wondered how the same species of plants could have different characteristics ID: 919761
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Slide1
Who was Gregor Mendel?
(And why was his work so important?)
Slide2Gregor Mendel
Gregor
Mendel was a monk who lived in the 1800s
Slide3Mendel’s Mind Wandered…
Mendel wondered how the same species of plants could have different characteristics
Characteristic
is a
trait
that makes the plant (and you) look a certain way
Mendel began to think…
Mendel wondered about the Characteristics
that
appeared with each generation
He wondered if they were “heritable
features
”
–
“Heritable” means they
are inherited
(passed
down)
from parents to children
Some traits appeared more often with
the same
parent plants
Mendel wondered why…
Slide5Pea Plants
Mendel performed an experiment and chose pea plants to use
He chose pea plants because he could identify
seven pairs
of contrasting traits found among
typical garden peas:
Seed color (yellow or green)
Seed shape (smooth or wrinkled)
Pod color (yellow or green)
Pod shape (inflated or pinched)
Flower color (purple or white)
Flower position (middle or end)
Stem height (tall or short)
Slide6Either or….
One or the other…
Easy to see AND collect data!
Slide7Watching the plants grow…
For two years, Mendel grew different varieties of peas to make sure that their offspring were always the same
This meant that the plants he used were
purebred
Purebred
means an organism always produces the same traits in its offspring
Slide8Think about purebred dogs…
When you purchase a purebred dog, you receive a record of their family tree so you know who their parents and grandparents and great grandparents were!Proof that the dog is purebred.
Slide9Patience is a virtue
After recording his observations over a couple of years, Mendel decided to breed different varieties together to make hybrids
Hybrid
means it’s a “mix
” -
a “cross
” -
of
different traits
(
Think… Hybrid cars!)
He made these hybrids by cross-pollinating plants with different characteristics
Cross-pollinating means “mating” (crossing) two different plants of the same species
White flower x Purple flower
Smooth pea x Wrinkled pea
Slide10Cross-pollinating (making hybrids)
Mendel brushed the pollen off yellow pea plants and put it on green pea plants
He did the same for plants with each of the seven pairs of traits
He then grew generation after generation of hybrids and tracked the appearance of the different traits
Slide11His Findings… Crossing Hybrids gives a
3 to 1 ratio of traits in offspring!
Slide12Crossing Characteristics
Mendel crossed many different traits and
carefully
recorded the traits of the
offspring
He determined that each parent supplies one
“
unit” or “factor” for each different
trait
…
S
omehow
…
Some traits seemed to disappear in the first generation but reappear later…
Slide13Recessive and Dominant
The traits that disappeared in the first generation of hybrids he called “Recessive.”
He called those that always appear, “Dominant.”
In later generations the recessive traits reappeared in a predictable pattern.
For example, later generations of plants had one green pea for every three yellow peas. The same ratio appeared for all seven pairs of traits.
Slide14Pea Soup Anyone?
Mendel grew an estimated 28,000 pea plants over eight years.
He recorded the traits of parent generations (P) as well as the traits of the first generation (F1)
(F1) is the “First Filial” generation: the first offspring to be born
Can you guess what the second generation was listed as? _____________
Slide15What Mendel Discovered
Mendel discovered that traits are inherited
And it occurs in a consistent pattern
Mendel used math to figure out what was going on in the cell and how the “factors” (traits) would be passed on.
See????? Math IS useful!!!!
Slide16The “Father of Genetics”
He published his results, observations and conclusions
These are now known as
Mendel’s Laws
Me
ndel's laws of heredity work with other organisms as well
They form the basis of modern genetics
Even though Mendel knew nothing about genes and DNA, we call him
the
“Father of Genetics”
Slide17Now called “Genetics”
Mendel used the terms “unit”, “factor” and “element” to describe how traits are inherited (passed) from parents to offspring
Today, we call these “units” GENES (DNA)
Genes are found on our chromosomes (in the nucleus of our cells) and are made up of DNA (which is made of nucleotides!)
Slide18What are Genes, Anyway?
Genes are the basic “unit” of heredity
They are a sequence of DNA that causes a certain characteristic to appear in an organism
Genetics is the science of genes, traits and heredity
Genetics
is the study of how traits are inherited (through genes) from one generation to another
Slide19The Punnett Square
Mendel found out that every trait is controlled by two “elements” (genes)
One from one parent and one from the other parent
Now, the “Punnett Square” is used to show how different traits are passed from one generation to the next
This is called
Probability
The chance that a given event will occur
Slide20Predictable Ratios
Mendel repeated his experiments over and over and the F2 generation always had a 3:1 ratio of yellow to green or round to wrinkly
Mendel then crossed plants that differed in more than one trait: round, yellow peas with wrinkled, green one, or tall, violet- flowered plants with short, white-flowered ones
These traits appeared in predictable ratios, too
Slide21Dominant & Recessive
Mendel determined that, in order to show-up, a
Dominant trait
needs only one trait “unit” from one of the parents
A dominant trait can “cover up” (mask) a recessive trait
Dominant is stronger, more powerful
The
Recessive trait
needs two “units”, from both parents, in order to show up in the next generation
Recessive is “weak”, possessing little power/influence
Slide22Mendel’s Laws of Inheritance
Mendel came up with these important conclusions known as
Mendel’s Laws
:
The
Law of Dominance
states that some unit characters can mask the expression of others.
The
Law of Segregation
states that each unit character separates into a different sex cell.
The
Law of Independent Assortment
states that genes segregate (separate) according to chance.
Slide23The Vocabulary of Genetics
The genetic make-up of an organism is called its “genotype”
It is the type of genes found in the cell
The appearance of the organism that is determined by its genotype is called its “phenotype”
It is how the organism looks (appears) on the outside
Slide24Homologous Pairs
When making a new organism, one gene from the mother matches up with a “similar” gene from the father
These genes are called “homologous” pairs
Homologous means similar (in length, size, genetic make up,
etc
…)
The homologous “genes” are found on chromosomes – so, if homologous genes pair up, they create homologous chromosomes!
Slide25Genes Vs. Alleles
A gene is a section of DNA which codes for a certain characteristic, such as height.
Genes, however, can have variations and this is where alleles come in…
Height can be either tall or short
Alleles are different versions of a gene.
For example, a tall allele or a short allele.
They are the different sequences of DNA that determine a single characteristic (height).
They occur in pairs (one from one parent, one from the other) and can be classified as recessive or dominant.
Slide26More Vocab!
Homozygous
means that the two alleles (genes) for an organism are exactly the same (TT or
tt
).
Also known as Purebred…
Hete
rozygous
means that the two alleles for an organism are different (Tt).
Also known as Hybrid…
Slide27Heredity
Heredity is the passing of traits from one generation to another”.
Inherited traits are passed (genetically), from the parent generation to the offspring
Slide28How do Geneticists figure it out?
Geneticists use letters to represent alleles.
The
same letter
is used to indicate both alleles.
A capital letter = a Dominant trait
A lowercase letter = a Recessive trait
Examples:
Flower color: P= purple, p= white
Seed color: Y= yellow, y = green
Seed shape: W = wrinkled, w = round
Slide29In humans….
Widow's peak: W = widow's peak, w = continuous hairline
Freckles: F = freckles, f = no freckles
Earlobes: E = unattached, e = attached
Thumbs: H = hitch-hiker, h = non-hitch-hiker
Cleft chin: C = cleft chin, c = no cleft chin
Hair on Fingers: F = hair, f = no hair
Spock Fingers: S =
spock
yes, s =
spock
no
Handedness: R = right handed, r = left handed
Slide30Slide31Slide32Slide33Genes & Mutations
Each gene carries a separate piece of information
DNA codes for all genes
Changes in the sequence of the DNA molecule (and therefore the gene) are called
mutations
A mutation may change the manner in which a trait is expressed by an organism.
So, a mutation in the genotype, changes the phenotype
Remember that not all mutations are bad!