PPT-Perfecting Complex Assemblies of Covalent and Supramolecular Polymers via Biological Principles

DMR 2104554 2021 Intellectual Merit Virgil Percec University of Pennsylvania Efficient viral or nonviral delivery of nucleic acids is the key step of genetic nanomedicine Both viral and synthetic vectors have been successfully employed for genetic delivery with recent examples being DNA adenoviral and mRNAbased Covid19 vaccines Fourcomponent lipid nanoparticles LNPs containing ionizable lipids phospholipids cholesterol for mechanical properties and PEGconjugated lipid for stability represent current leading nonviral vectors for mRNA a We reported the development of a onecomponent multifunctional ionizable amphiphilic Janus dendrimer . Ch. . 16. Covalent Compounds. Covalent bonds. form when atoms share . their valence electrons. .. Covalent compounds. are formed from 2 or more nonmetals.. Rules for Naming Covalent Compounds. 1. Prefixes are used to show how many atoms of each element are present in the compound . VSEPR Theory, Polarity, and using . Electronegativity. Covalent . Bonds. Forms when 2 atoms share a pair of valence e. -. A. Types of Covalent Bonds. 1. . Single Covalent Bond . – two atoms share . Co = Together. The Octet Rule. The octet rule says that all atoms want to have eight valence electrons, like the noble gases.. One way that atoms can follow the octet rule is by giving and taking electrons… ionic bonding. Chapter 9 ~ most compounds, including those in living organisms, are covalently bonded. What You’ll Learn. I will analyze the nature of a covalent bond. I will name covalently bonded groups of atoms. Including Naming. Note: We likely won’t make it to covalent nomenclature, this is the one students find FAR easier than ionic. Please refer to the videos and naming hand out for help with this, and as always office hours, discussions, and . COVALENT BOND. bond. formed by the . sharing . of . electrons . Covalent . Bonds. Between nonmetallic elements of similar electronegativity. .. Electronegativity = how badly an atom wants to add an electron (non metals have higher electronegativity). C2: Chapter 2. Learning Objectives. To be able to . list. and . state. uses of commonly used polymers. To be able to . recall and describe. the conditions required for the production of LDPE, HDPE, thermosetting and thermosoftening polymers. Biochemistry. 1. What is Biochemistry?. Biochemistry = chemistry of life. . Biochemists use physical and chemical principles to explain biology at the molecular level.. Basic principles of biochemistry are common to all living organism.  . 1) . SeF. 6. . . ________________________________________.  . 2) . TeO. 3 . . ________________________________________.  . 3) . H. 2. O. . . ________________________________________.  . By: Andres F Sanchez. Molecular Orbital!. Molecular Orbital- . The space that shared electrons move in. Covalent Bond- . when two atoms share electrons. Energy and Stability. Most atoms have low stability except noble gases. Ionic bonds . result when electrons are transferred between atoms. Covalent bonds . result when valence electrons are shared between atoms. Types of Bonds. Formed between a . metal. and a . non-metal. Mrs. Page. Essential Idea. Lewis (electron dot) structures show the electron domains in the valence shell and are used to predict molecular shape. .. Nature of Science. Scientists . use models as representatives of the real world – the development of the model of molecular shapes (VSEPR) to explain observable properties.. Covalent Bonds. Covalent bonds:. occur between two or more . nonmetals. ; electrons are . shared. not transferred (as in ionic bonds). The result of sharing electrons is that atoms attain a more stable electron configuration.. Covalent bonds . result from the . sharing . of electrons. between two atoms.. A covalent bond is a . two-electron bond . in which the bonding atoms share valence electrons.. A . molecule . is a discrete group of atoms held together by covalent bonds..