PPT-Immunosuppression for Kidney Transplantation

Fellows Conference Immunosuppressive Medications Slide courtesy of Dr MeierKriesche ThreeSignal Model Halloran N Eng J Med 20043513715 Immunosuppressive Medications Induction Corticosteroids. Immunosuppression Stacey Geisel. The University of Central Florida. KIDNEY TRANSPLANTATION OVERVIEW. Surgical procedure to place a healthy kidney from a live or deceased donor into a person whose kidneys no longer function properly. Introduction . Patients who undergo renal transplant require complex care. Diligent, multidisciplinary approach. Knowledge of patient’s history pre-, during and post-transplant. Surgeons, Nephrologist, consultants, PCP and allied health professional all work to direct transplantation efforts and . Juan Carlos Caicedo, MD FACS. Di. rector, Hispanic Transplant Program. Adult transplant Surgeon (NMH). Pediatric Transplant Surgeon (LCH). Overview. Introduction . Kidney ( Living / deceased/ combined stem cell). HISTORICAL DEVELOPMENT OF TRANSPLANTATION. . Experiments with organ transplantation started in. 19th century but were unsuccessful due to bad. surgical techniques and lack of knowledge on immune incompatibility. 1. History . Since early times the idea of tissue and organ transplantation has captured the imagination of successive generations. Early attempts at organ transplantation were ended with failure due to . . . . Pathogenesis of EBV Infection. . Cohen . NEJM 2000. Early IM: NK cells. non-HLA specific CTLs. Late IM: HLA-restricted CTLs (CD8 and CD4):. Lytic epitopes - up to 40% of CD8 cells . Introduction. Kidney transplantation (KT) is the best renal replacement therapy for many patients with End Stage Kidney Disease (ESKD) . Knowledge about KT helps patients make more informed treatment decisions. Milan Kinkhabwala, MD. Professor of Surgery . Director of Abdominal Transplantation. Montefiore Einstein Center for Cancer Care. History of Transplant. Understanding of . Alloimmunity. : Medawar et al 1950’s. Cardiac : Eligibility and Listing Criteria in Canada 2012 1 Cardiac Transplantation: Eligibility and Listing Criteria in Canada Debra Isaac MD, Michael Chan MD, Haissam Haddad MD, Anson Cheung MD, . Is . transplantation a final end, or a new start?. 10302010078 . Liu . Wangyuan. Key Words. Allograft: . grafts transplanted between individuals of the same species. MHC:. major histocompatibility complex. Transplant or dialysis ?. . Christie P Thomas MD. Professor and Vice Chair, Faculty Advancement. Department of Internal Medicine. Medical Director, Kidney Transplant Program. University of Iowa Carver College of Medicine. transplantation - the . role of. desensitization . protocols. Milica . Kravljaca. Clinic of Nephrology University Clinical Center of Serbia. Faculty of Medicine University of Belgrade. What are the key challenges in kidney transplantation today?. I. PAÚ. Transplantation. Transfer . of. . living. . tissue. . Cells. : stem . cells. , . blood. . cells. – . platelets. , …. Tissue. : . blood. , bone . marrow. , skin, bone, . cartilage. , .