PPT-Cyclosporine Because

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PHARMACOKINETICS Slideshow by lecturer HADEEL DELMAN THERAPEUTIC AND TOXIC CONCENTRATIONS The therapeutic range of cyclosporine depend on the type of assay used

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Cyclosporine Because: Transcript


PHARMACOKINETICS Slideshow by lecturer HADEEL DELMAN THERAPEUTIC AND TOXIC CONCENTRATIONS The therapeutic range of cyclosporine depend on the type of assay used to measure cyclosporine concentration. CAQCORNER OLT,orthotopiclivertransplantation;CNIs,calcineurininhibitors;CyA,cyclosporine;TAC,tacrolimus;IL,interleukin;MMF,mycophenolatemofetil;MPA,mycophenolicacid;ATG,antithymocyteglobulin;RAP,Rapam Jennifer N. Fosnot, Pharm.D.. Nurse Practitioners Symposium. Nashville, TN. September 27-28. th. , 2012. Objectives. 1.) Discuss the CYP 450 enzymes and common drug interactions with the immunosuppressants. August, 2014. Immunopharmacology. Munir Gharaibeh, MD, PhD, MHPE.. August, 2014. Immunopharmacology. Immunosuppressive Agents.. Immunomodulation Therapy.. Immunologic Reactions to Dugs.. Immunosuppressive Agents. 26 26 26 26 6 6 6 CH CH CH H RO RO RO RO RO O N NI NI NI NI N C C C C C FE FE FE FE FE FE FE L LI LI LI LI I LI NE NE NE NE E E G G G G G G G IN IN IN IN I N GI GI G GI G I VO V VO V VO V O ST ST ST Fellows Conference. Immunosuppressive Medications. Slide courtesy of Dr. Meier-Kriesche. Three-Signal Model. Halloran, . N Eng J Med. , 2004;351:3715. Immunosuppressive Medications. Induction:. Corticosteroids. by: lecturer HADEEL DELMAN. Cyclosporine. …. Therapeutic . and Toxic . Concentrations . The . therapeutic range of cyclosporine . depend on:. The . type of assay used to measure . the concentration.. Pharmacology III. Immunosuppressive drugs are useful in: . a) Treating autoimmune diseases; and . b) Preventing . immunorejection. of organ transplants.. Immunosuppresants. may be classified as-. Calcineurin inhibitors: Cyclosporine Tacrolimus . MD. ASSTT. PROFESSOR. DEPTT. OF MEDICINE. Aplastic. anemia is . pancytopenia. with bone marrow . hypocellularity. .. M. en and women are affected with equal frequency.. A. ge distribution is biphasic, with the major peak in the teens and twenties and a second rise in older adults.. Anna Koget, D.O. . Aplastic Anemia . An . acquired. stem cell disorder . Idiopathic (unknown etiology) in 70% of the cases . Diagnosis of exclusion . Important to differentiate from other causes of Bone Marrow Failure .

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