PPT-CRISPR Babies: Background and Ethics

CRISPR Babies Background and Ethics By Austin Guse and Kaitlyn Curtis What is a CRISPR baby An organism specifically a human child that has had its genetics altered in one way or another and has successfully been born or is still in guestation. Youll 64257nd updates on MWing construction as well as news of interest to Women Babies staff If you have any suggestions for future content please drop a line to sandeepdeolsunnybrookca or call 4169678554 One Night Live Host Chris Noth Visits Wome DeMayo. FJ, Spencer TE. Jennifer Thornton. April 1, 2015. Happy April Fools’ Day!. *I won’t actually cover this paper, but it’s real and you should check it out at. http. ://www.ncbi.nlm.nih.gov/pubmed/25100711. Introduction to CRISPR. http://. www.addgene.org. /CRISPR/guide/. Wiedenheft. et al. Nature 2012. 3 distinct types of bacterial CRISPR systems identified so far:. Type I, II, III . Type II is the basis for current genome engineering applications. Presented By :. Amna. Muhammad. 09-Arid-1536. Ph. D Scholar . Biochemistry. 1. st. Semester. 12/16/2014. 1. Contents. History. Functional analysis of a gene. RNA . interfernce. . siRNA. shRNA. miRNA. - through the lens of the IRB -. P. Pearl O’Rourke, MD. Partners HealthCare. Boston, MA. Context:. Institutional Review Board (IRB). Charged with the oversight of . human subjects . research. Common Rule, definition of human subject : . Type . III-B to . Target RNA Encoded . Viruses infecting humans. . Presented By: Diana Marquez. Rhinovirus. Common cold. Impacts adults 2-3 times a year and children 6-10.. Introduction. + stranded RNA virus.. The Wonderful World of CRISPR. As told by Professor Peter Shepherd. To do precise genetic engineering we need to be able to find and specifically modify regions of DNA. But the human genome has 3,000,000,000 base pairs so how are we going to find a 20 base pair region in this huge sea of DNA ? . Viruses. . Presented By: Diana Marquez. Introduction. The Rhinovirus, while often synonymous with the “common cold” has also been found to be a contributing factor for the occurrence of acute respiratory conditions such as asthma and inhibit effective infection resolution in at risk individuals. CRISPR and Viral Diagnostics Susan Eiben Jun Huang Kira Slepchenko https://www.youtube.com/watch?v=22F85FOAyik CRISPR-Cas9 https://labiotech.eu/features/crispr-cas9-review-gene-editing-tool/ Clusters of Regularly Interspaced Short Palindromic Repeats Genomics. Lesson 12, presentation 3. Hardison. (several slides . from Dr. . Cooduvalli. . Shashikant. ). 4/26/15. 1. Genome Editing . Removal, modification, or addition of a functional element into the genome of a living cell or organism. FucU CRIPR/Cas9 KO Plasmid (m): sc-427279 Santa Cruz Biotechnology, Inc. 1.800.457.3801 831.457.3800 fax 831.457.3801 Europe + 00800 4573 8000 49 6221 4503 0 www.scbt.com BACKGR The primary Sigma product number covered by this technical bulletin is:CRISPR for: Custom gRNA expression plasmids (including All-in-One and gRNA-only plasmids) T7-generated gRNA Lentiviral particl Retina Summary of Grant Activities: January to December 2015 Project Title: Correcting inherited retinal disease through gene editing . Research Team: Dr Sandy Hung, Dr Raymond Wong, Dr Kathryn D [Abusive Head Trauma in Babies] . 7 MINUTE BRIEFING - To be shared at Team Meetings . Abusive Head Trauma (AHT) -also known as Shaken Baby Syndrome- is . child abuse. . It results in catastrophic injuries or death. Around half of severely injured...