PPT-Intro to Probability & Genetics

Vocab reminders Genes are located at a particular place on DNA locus Focus on one locus Each partner in a homologous pair one from mom one from dad has the same gene at that locus The gene might vary thoughan . Whenthegoalis... ...usetactic verysimple auto,tautoorfirstorder p/\q split p\/q leftorright p-q intro ~p intro pq split anassumption assumption forallx,p intro existsx,p existst TousehypothesisH... Martina Litschmannová. m. artina.litschmannova. @vsb.cz. K210. Probability . basics. Statistical. (. random. ) experiment. A . r. andom. experiment . is an action or process that leads to one of several possible outcomes. . We are flipping 3 coins and the outcomes are represented by a string of H’s and T’s (HTH, etc.). . How many elements are there in the sample space?. Express the event “There are more heads than tails” as a set.. be used being replaced changes in narios for accurate. These results beneficial mutations Fixation Probability be based derived from following sections, 726 S. P. Otto and M. C. Whitlock TABLE 1 Th We are flipping 3 coins and the outcomes are represented by a string of H’s and T’s (HTH, etc.). . How many elements are there in the sample space?. Express the event “There are more heads than tails” as a set.. Next Generation Sequencing:. A technical perspective. Bristol Genetics Laboratory. Joanne Davies. Genetic Technologist. Objectives. Summarise the NGS assays currently available at BGL. Look at the general challenges with NGS assays. Next Generation Technology . Developments and Applications:. Now and Potential across Healthcare. Eileen Roberts. Thalia Antoniadi. http://www.nbt.nhs.uk/genetics. The changing landscape . Advances in technology are altering the landscape of medical care . 4 Misconceptions. “Christianity must be proven scientifically”. Scientific Method:. - Controlled Environment. - Experiment. - . Repeateable. . Legal/Historical Method:. - Written. - Oral. - Physical. Big Ideas of this Chapter!!. Inherited genes determine an organism’s traits. . Using scientific methods, . Gregor. Mendel discovered the basic principles of genetics. . It is now known that interactions among alleles, genes, and the . How are traits passed down from parents to offspring?. Concept 1. : Analyzing the effects of classic . Mendelian. genetic crosses such as . monohybrid, . dihybrid. , testcross. , and applying to . pedigree. Gene. Allele. Population. Gene . pool. Population Genetics. Starter - write biological definitions for the following key words:. Gene – a section of DNA that codes for a particular . protein/polypeptide. 1. . Discovered . by James Watson and Francis Crick . in 1953. 2. . Stores . genetic information for the production of proteins. 3. . Composed . of nucleotides. A) . A . nucleotide is composed of a nitrogenous base, . Conclusion:. Heredity material was packaged in discrete transferable units; came up with law of segregation and law of independent assortment.. Thomas Morgan – early 1900’s. Discovered that fruit flies’ genes were associated with chromosome inheritance.. Early ideas about genetics. Hippocrates:. Pangenesis. Particles (. pangenes. ) from each part of the body moved to the egg and sperm. Changes in organisms over their lifetime would be passed on to offspring .