PPT-Topic 2.6 Structure of DNA and RNA

Essential idea The structure of DNA allows efficient storage of genetic information 26 Structure of DNA and RNA Nature of science Using models as representation of the real worldCrick and Watson used model making to discover the structure of DNA 110 . DNA: Picture 51. http://info.bio.cmu.edu/courses/03231/ProtStruc/ProtStruc.htm. B-DNA: The advent of modeling. http://molvis.sdsc.edu/pdb/dna_b_form.pdb. 46 Å. . 12 base sequence. (1953-2003). DNA: Size, Shape & Self Assembly. DNA from a few Angles. Cell: . Every cell contains a nucleus which is filled with the directions for cell function, DNA. . Chromosome. : . When DNA is tightly coiled and wound it becomes visible in the form of . Stryer. Short course. Chapter 33. Nucleic Acid Structure. Nucleobase. Nucleoside. Nucleotide. Nucleic acid. Chromatin. Chromosome. Polymeric Structure. Polymer ideal for informational molecule. Ribose and deoxyribose. Add to Table . of Contents. p. 10 DNA/RNA Vocabulary. p. 11 DNA/RNA Structures. p. 12 Complementary Base-Pairing. DNA. Deoxyribonucleic Acid. Double-stranded. Double-helix structure. Made of nucleotides - each nucleotide has 3 parts (remember PBS). 2.6 Structure of DNA & RNA. Understandings:. The nucleic acids DNA & RNA are polymers of nucleotides.. DNA differs from RNA in the # of strands normally present, the base composition & type of pentose.. Essential idea: The structure of DNA allows efficient storage of genetic information.. There is 2m of DNA in each human cell, however the most cells in the human body have a diameter of 10 . μm. . This DNA is divided in chromosomes and coiled around proteins called histones so that it can be efficiently stored in each cell's nucleus. The human genome project which has decoded the case sequence for the whole 2m of the human genome requires a data warehouse (pictured) to store the information electronically. This should give a good idea of just how efficient DNA is at storing information and why it needs to be so.. CHM . 341. Suroviec. . Fall . 2016. I. . Nucleotides, Nucleic Acids and Bases. Bases. Planar, aromatic, heterocyclic. Purine (2 rings). Pyrimidine (1 ring) . Adenine (A). Guanine (G). Thyamine (T). Where do we find DNA?. How do crime scene investigators use DNA to solve crimes? . NUCLEIC ACIDS. Flow of biological information: . DNA . RNA. protein . trait. DNA . deoxyribonucleic acid. Transformation. 1928- . Frederick Griffith . was trying to figure out how bacteria made people sick. Pneumonia. Cause of pneumonia was not a chemical poison released by disease causing bacteria. The heat killed bacteria had passed their disease-causing ability to the harmless strain. Jianlin Cheng, PhD. Department of EECS. University of Missouri, Columbia. Spring, 2019. The Genomic Era. Collins, Venter, Human Genome, 2000. DNA Sequencing Revolution. Scientists. Government. Company. (Chapters 6 and 3). . Presented by Dr. Laurie M. Erickson. Chair of the Department of Health Sciences. Blitstein Institute of Hebrew Theological College. Chicago, IL, USA.. 1. 6.1 Genome Size. Genome:. .. The length of the transcription bubble is about 12 to 14 . bp. , but the length of the RNA–DNA hybrid within the bubble is only 8 to 9 . bp. . As the enzyme moves along the template, the DNA duplex reforms. Mitosis, Protein . Synthesis. Week 8. 9/29 . DNA Replication . 11.1. Obj. TSW demonstrate base pairing rules of DNA Replication by constructing a 2-D model of DNA with paper. . P. 68 NB. Replication Video. 1. The Gutell . Lab @ The . University of Texas at . Austin. Major Topics. Importance of RNA in the Cell. Major Changes in Paradigms. . Grand Challenges in Biology. Identification and Characterization of RNA Structure.