PPT-Integration of Novel Therapies in WM and CLL : When and How

Neil E Kay MD October 2014 Mayo Team Deb Bowen Tim Call Michael Conte Wei Ding Tait Shanafelt Steve Ansell Learning Objectives Review standard therapies of WM and CLL C an we still consider standard therapies in WM and CLL. Impact . on t. iming . of . therapy. Nicholas Chiorazzi. The Feinstein Institute for Medical Research. North Shore – LIJ Health System. Manhasset, NY. At all points in time, CLL clones are heterogeneous based on a number of criteria. Ibrutinib. Sensitivity and Resistance in CLL. Y. Lynn Wang, MD, PhD, FCAP. Dept. of Pathology. University of Chicago. October 24, 2014. Outline. Ibrutinib. targets . in vivo CLL proliferation through . Spring 2010. Clinical history. A 62 year old man presents to his primary care physician with lymphadenopathy. . A CBC demonstrates the following: . WBC 20.73 thousand cell/microliter . 12% neutrophils. Insight Therapies. Relationship Therapies. Behavior Therapies. Cognitive Therapies. Biological Therapies . Evaluating the Therapies. Culture- and Gender- Sensitive Therapies. Why Seek Therapy?. Approaches to Therapy. Enhancing phototherapy . Jane emmonds/Andrea ward. What are they ?. Topical therapies are medications that are applied to a particular place on or in the body, as opposed to systemically.. Topical derives from . Medical Director, Heart Failure and Cardiac Transplant Program. University of Pennsylvania. What Are Advanced Therapies?. Heart Transplant. Ventricular Assisted Devices (VAD). Mechanical Circulatory Support (MCS). Over the ages, a mix of treatments and . methods . have. been attempted . to . treat people . with . psychological. disorders. Treatments . have. ranged . from harsh to gentle. Reformers. Philippe . Mary-Margaret Allen, MD. February 24, 2015. 58 . yo. male with a history of CLL (2008). Later developed AIHA 2/2013. P. rednisone taper (Feb to May 2013). Recurrent 9/2013: . rituxan. and quick steroid taper. CLL Stromal cell protect Conventional therapies Versteckspiel im Wald by Friedrich Eduard Meyerheim (1808-1879) The “outside ” (microenvironment) of the CLL cell: new insights into disease Unit Objectives Approx 15 week per unit New Essential standards Words/Structures Resources Unit 1 Salut a va Greet someone Introduce yourself Introduce someone else Ask someones name Tell someones na Rouslan Kotchetkov. ,. MD, PhD. 1. , Erin Ellison, MD. 2. , . McLean J, PhD. 1. , Bryn . Pressnail, MD. 1. , Derek Nay, MD. 1. .  . 1. Simcoe . Muskoka. Regional Cancer Program. , . 2. Department . Title: Chronic Lymphocytic Leukemia by flow cytometry: an European Research Initiative on CLL ( ERIC ) & European Society for Clinical Cell Analysis ( ESCCA ) harmonisation project Running title crash course. "Bring Me To Life"-therapy; start @ 24:24. Philippe Pinel. French doctor who was the first to take the chains off and declare that these people are sick and “a cure must be found!!!”. Mallaig. Sprinkling Song . Spirit of God, come dwell within me..  . Open my heart, O come set me free. . Fill me with love for Jesus, my Lord.. O fill me with living water.. Jesus is living, Jesus is here. .