PPT-Updates on T-cell lymphoma

Dr Stefan K Barta University of Pennsylvania USA July 2020 2 Please note The views expressed within this presentation are the personal opinions of the author They do not necessarily represent the views of the authors academic institutions or the rest of the LYMPHOMA CONNECT group. Lymphoma is divided into two major categories Hodgkin lymphoma HL and nonHodgkin lymphoma NHL Mantle cell lymphoma MCL is one of about 70 di64256erent subtypes of NHL Lymphoma may arise in any one of three types of lymphocytes B lymphocytes B cells Common (West), low-grade B-cell lymphoma. Affects elderly. Arises from germinal center B-cell. Lymphoma cells have specific translocation t(14:18), in which Bcl2 gene on chr18 fuses with . IgH. gene on chr14, causing . Therapeutic Targets in CLL. Venetoclax in Patients With 17p Deletion. Venetoclax in Patients With 17p Deletion (cont). Bendamustine Plus Obinutuzumab. Ibrutinib Plus Ublituximab. Updates in Lymphoma From Recent Congresses. Program Goals. DLBCL Subtypes . 2008 WHO Classification. Other DLBCL Variants. Dissecting DLBCL into Molecularly and Clinically Distinct Subgroups by Gene Expression Profiling. Outcomes Based on DLBCL Subtype Using Gene Expression Profiling. Zahra Mozaheb MD. Assistant professor of Hematology-Oncology . Mashhad University of Medical Science. Iran Mashhad. “5th world Hematologists congress" . Lymphoid malignancies are remarkable and. . Non-Hodgkin’s lymphoma (. NHL) is a term covering all . lymphoproliferative. system malignancies except Hodgkin's lymphoma . The disease is rare in subject under 30 years of age and incidence increase with age . Around two-thirds of all cases are diagnosed in people over 60 years . . Jarrod Troy ISU-CVM Class of 2014. 416 Billy Sunday Rd Apt. 101. Ames IA 50010. Mentor: . Stephanie Caston, DVM, DACVS-LA. Iowa State University Equine Surgery Service. Case Previously Presented by R David Whitley, DVM, MS, DACVO. MODERATOR : DR. GANAPULE . Definition . Lymphomas are malignant . tumours. of lymphoid tissue which give rise to solid tissue masses.. Heterogenous. group of disorders.. HODGKINS LYMPHOMA. NON-HODGKINS. Helpline: 800 500 9976 | helpline@lymphoma.org Understanding LymphomaDiffuse Large B-Cell Lymphoma: Relapsed/Refractory Diffuse large B-cell lymphoma (DLBCL) is the most common form of non-Hodgkin l DiagnosisThe diagnosis of lymphoma is many times straightforward. Definitive diagnosis can be obtained by either cytologic or histopathologic evaluationof the affected organ system. Because multicent Overview Case 3 • 59 year old man with lymphadenopathy in the neck, supraclavicular area, inguinal area . He states that he has had LN for at least 18 months and they have waxed and waned . Dr. Sanne Lugthart. (. Dr. Stephen Robinson). University Hospital Bristol. 20 June 2019. Scope Of Talk. Current CAR T products available for NHS patients. The CAR T pathway (up to re-infusion). Patients Cases. . leukaemia. CLL-related conditions. Monoclonal B-cell . lymphocytosis. (MBL. ). Small lymphocytic lymphoma (SLL. ). Richter’s syndrome (RS). Richter’s syndrome (RS) represents the development of an. Prof. . Alexey V. Danilov, MD, PhD,. 1. Dr. Massimo . Magagnoli. , MD,. 2 . Dr. Matthew J. . Matasar. , MD. 3. . SELECTED HIGHLIGHTS. 1. City of Hope National Medical Center, Duarte, CA, USA; . 2. Humanitas Cancer Center, .