PPT-The Genetics and Molecular Biology of Huntington’s Disease

Son Dong Justin Wise Niket Yadav History Confusing disease in mid 1 6 00s Had different names based on symptoms First mention was in 1842 Major discoveries occurred after Charles Gorman Johan Lund. Facts & . Achievements. "Biochemistry brings molecular science to life". . 1. 2. Introduction. Education and Research – organizational . structure. Educational offer. National . and international visibility. Beach Fire Pits & Fireplaces. HBFIREPITS@YAHOO.COM. SMOKELESS & ECO . -. GREEN. . PORTABLE & AFFORDABLE. COME SEE OUR NEW STORE . CALL TODAY TO SET YOUR APPOINTMENT. VINNI D. FIREGUY . The Big Epigenetic Event. Males – 46,XY. Females – 46,XX. Compensate for gene dosage, all mammals inactivate extra X chromosome. Discovered by Mary Lyon. Lyon, M.F., 1961. Gene action in X-chromosome of the mouse (. Josiah McFarland, . Mattina. . Girardot. , Elaine Platt. Huntington’s Disease Treatments and Therapies . No treatments, medications, or therapies can cure HD or alter the course of the disease . The disease cannot be stopped or slowed down at this point, only maintained. MOLECULAR BIOLOGY TECHNIQUES II.. Polymerase Chain Reacton – PCR. DNA sequencing. Amplification of specific DNA fragments. MOLECULAR BIOLOGY – PCR. Cloning and/ or isolation from a genomic library . II 1 2 3 4 5 6 7 8. III. . 1 2 3 4 5. Which members of the family are afflicted with Huntington’s disease? . Richard H. Lathrop. Dept. of Computer . Science. Univ. of California, Irvine. rickl@uci.edu. Donald Bren Hall 4224. 949-824-4021. “Computers are to Biology as Mathematics is to Physics.”. --- Harold . Department of Biochemistry and Molecular Biology Today Facts & Achievements "Biochemistry brings molecular science to life" 1 2 Introduction Education and Research – organizational structure Filipa Mendes. Center. for Nuclear Sciences . and. Technologies. IST, Universidade de Lisboa .  . Summer school . Development and Pre-clinical Evaluation of Radiopharmaceuticals. Molecular . and. Cell . Institute of Medical S ciences (IMS) Banaras Hindu University (BHU) Varanasi - 221005 Junior Research Fellow Applications are invited for the one post of the Junior Research Fellow ( JRF ) with a s Huntington Society of Canada 151 Frederick St., Suite 400, Kitchener ON N2H 2M2 1-800-998-7398 info@huntingtonsociety.ca www.huntingtonsociety.ca Charitable Registration Number 11896 5516 RR0001 Wh Department of Biology and Department of Bioengineering, The University of Pennsylvania, Philadelphia, PA*Authors for correspondence (e-mail: zhqi@sas.upenn.edu; markjo@seas.upenn.edu) Hunting for the ;. . the. . study of . biology. at the . molecular. level.. Molecular biology. ;. . the. . study of . gene . structure and functions at the . molecular level. . to understand the molecular basis of hereditary, genetic variation, and the expression patterns of genes. . Dr. Sonalika’s Eye Clinic provide the best Corneal disease treatment in Pune, Hadapsar, Amanora, Magarpatta, Mundhwa, Kharadi Rd, Viman Nagar, Wagholi, and Wadgaon Sheri