PPT-Adaptive Responses of Natural Killer Cells Exhibit Distinct Requirements Among Members

Gayani S Gamage 1 Daniel MedinaLuna 1 Michal Scur 1 Hagaag S Zein 1 Mir Munir A Rahim 2 Brendon D Parsons 1 Andrew P Makrigiannis 1   1 Department of Microbiology and Immunology Faculty of Medicine Dalhousie University5850 College Street Halifax B3H 4H7NS Canada. Zoran . Galic. Ph.D. .. Division of Hematology/Oncology. David Geffen School of Medicine UCLA. zgalic@ucla.edu. August . 11, 2015. In response to pathogens, vertebrate immune systems use two interconnected systems:. J S Brown. Reader in Respiratory Infection. Centre for Respiratory Research. Department of Medicine. University College London. incidence: overall 0.25%? . admissions 50/100,000 per year > 65 years. General principles of host defense. Mechanisms . of host defense against different classes of microbes . Immune evasion by microbes . Injury caused by normally protective immune responses . Strategies for vaccines . Cell and its Role in Adaptive Immunity and Cancer Immunotherapy. Amna. Muhammad. Ph. D scholar. Biochemistry. 1. Contents. Introduction. Dentritic cell and control of immunity. Immunity. Antigen Presentation to T cells. Clinical Commissioning Group Workforce Equality & Diversity Profile. December 2014. Contents. 2. Slide. no.. Slide no.. Introduction. 3. Religion or Belief. 16. Data Coverage. 4-5. Sexual Orientation . the Clinic. The V Foundation. May 2. nd. , 2016. Michael A. Caligiuri, MD. Human large . g. ranular lymphocytes or natural . k. iller (NK) cells. Human . NK cell . subsets. NK cell receptor biology. Clinical application of. Kuby. . Immunology. , . 7e: Chapter 1. A historical perspective of immunology. What is immunity?. Immunity is the state of protection against foreign pathogens or substances (antigens). Latin term . Page 1 of 9 H K$ 0. 6 7 Target p rice: HK $ 0. 8 6 Up side: 28 . 3 % Hayman Chiu h ayman .chiu @cinda.com.hk (852) 2235 7 677 Trading data 52 - Week Range (HK$) 3 M t h Avg Daily Vol (m) No of Share 1. st. Lecture. Definitions. Immunity. . (. Latin . “. immunitas. ”) is a universal biological phenomenon that develops many programs based on the unique genotype of the body (“self”) in foreign surroundings, from the birth of the body to its death. There are two major types of immunity, . Immune Response. Adaptive Immune. 2. Adaptive or Acquired Immune Response. Protects against infectious agents and abnormal body cells . Amplifies the inflammatory . response. Activates complement. 3. , . their. . characteristics. . and. . function. . . Interferons. .. 9. HLA . system.   (. classes. , . polymorphism. , . typing. ).. 10. . Binding. . of. . peptides. to MHC. Antigen . presentation. Natural . killer (NK) cells are large granular lymphocytes that, like CTLs, use cytoplasmic granules containing . perforins. to kill target cells. NK cells . were defined . initially by their ability to lyse certain tumor cell lines and virally infected cells in vitro. In contrast to T cells, NK cells can lyse these cells without prior immunization, and so mediate a form of innate (or natural) immunity that is termed . Features of adaptive immunity:. Adaptive immunity is characterized by the following:. 1. Antigenic specificity: (. highly specific).. 2. Diversity : . ( each antigen there is specific T-cell and B-cell for it).. Organs and . cells. Peter Kelleher. Senior Lecturer, Imperial . College London, . Chelsea & Westminster . campus. Learning objectives . Illustrate the importance of immunology for human health..  .