PPT-Benchmarking Statistical Multiple Sequence Alignment

Tandy Warnow Joint with Mike Nute and Ehsan Saleh https wwwbiorxivorg contentearly20180420304659 Performance Study on bioRxiv Goal Evaluate BaliPhy Redelings and Suchard on both biological and simulated datasets in comparison to leading alignment methods on small protein sequence datasets . Jia. -Ming Chang, Paolo Di . Tommaso. , and Cedric . Notredame. TCS. : A new multiple sequence alignment reliability measure to estimate alignment accuracy and improve phylogenetic tree . reconstruction, . Tandy Warnow. The Department of Computer Science. The University of Texas at Austin. The “Tree of Life”. Avian Phylogenomics Project. G Zhang, . BGI. . Approx. 50 species, whole genomes. 8000+ genes, UCEs. Xuhua Xia. xxia@uottawa.ca. http://dambe.bio.uottawa.ca. Xuhua Xia. Slide . 2. Normal and Thalassemia HBb. Are the two genes homologous?. What evolutionary change can you infer from the alignment? . What is the consequence of the evolutionary change?. with. PASTA. Michael Nute. Austin, TX. June 17, 2016. Agenda. Quick recap of PASTA Algorithm. Run the GUI. Explore GUI options and what they do in terms of PASTA. Run a test alignment. Explore PASTA outputs and diagnostics. Maya Schushan. November 2010. Outline- introduction to alignments. 1. . Introduction. 4. Pairwise Alignment:. Smith-Waterman. Needlman-Wunch. 5. Multiple Sequence Alignment:. ClustalW. MUSCLE. T-coffee. : . Improve Energy and Operational Efficiencies Throughout Your Portfolio. Jeff Gerwig. Colliers International. Emily Pearce. Waypoint Building Group. What is Benchmarking?. Value of Benchmarking for Commercial Real Estate. . You have learned about:. Data & databases. Tools . Amino Acids. Protein Structure. Today we will discuss: . Aligning sequences. After this: . You know how to perform structural alignments. BMI 877. Colin Dewey. colin.dewey@wisc.edu. March 14, 2017. Overview. What does it . mean . to . align. sequences?. How do we cast sequence alignment as a . computational problem?. What . algorithms . Assessment, Improvement and Accountability. Michelle Taylor| Senior Research Analyst. National Higher Education Benchmarking . Institute. Steps to productive benchmarking.. Productive Benchmarking. Simply put, benchmarking is comparing your college to other colleges. Liz Boone, RD, LD, MBA. Corporate Dining, Inc.. What is Benchmarking?. The process of comparing one’s business process and performance metrics to industry bests or best practices from other companies. Tandy . Warnow. Studies we will discuss. Katoh. and . Standley. , MBE 2013 (about MAFFT). Nelesen. et al., PSB 2008 (Impact of guide tree). Liu and Warnow, . PLoS. ONE 2012 (about treelength criteria). Jia. -Ming Chang, Paolo Di . Tommaso. , and Cedric . Notredame. TCS. : A new multiple sequence alignment reliability measure to estimate alignment accuracy and improve phylogenetic tree . reconstruction, . ClustalW. Note. : EBI has retired the ClustalW service; see the new presentation "Generating Multiple Sequence Alignments with Clustal Omega" . ClustalW: . creating a multiple sequence alignment. You identify sequences to align. the role of gene duplication followed by loss of function in speciation. For Friday, go through the slides from class 11. Aligning sequences is part of many analytical pipelines . Alignments can be local or global.