PPT-Redox behavior of central-acting opioid Tramadol and its possible role in oxidative stress

Uriel Abe Contardi 1 Mateus Morikawa 1 and Douglas Vieira Thomaz 2 1 Federal University of Technology Paraná 2 Federal University of Goiás Correspondence douglasvthomazgmailcom. Titration. OF bleach . Due Today: . 1. Redox Titration of Bleach Pre-Lab. 2. . Copper Reduction Formal Lab Report. Homework:. 1. Redox . Titration . Short Report. 2. Gravimetric Analysis of Phosphorus Pre-Lab. Tramadol is a narcotic pain killer that is prescribed for the management of moderate to severe pain. Its immediate release formulation provides relief around the clock which is mainly prescribed for the ongoing chronic pain. Tramadol 50mg is an oral dosage form used to moderate to severe pain of the body. It belongs to the category of medicine termed as synthetic opioid analgesic. It is approved by FDA in March 1995 and is classified as a Scheduled 4 controlled substance under the Controlled Substance Act. Definition. If oxidation occurs, then reduction must also occur. Any chemical process in which elements undergo a change in oxidation number is a . Redox reaction. Example. 2Na + Cl. 2. . → 2Na. Oxidative Stress. O. 2. is readily reduced to form one of many Reactive Oxygen Species (ROS) . ROS cause cellular damage. DNA. Protein. Lipids. http://www.vivo.colostate.edu/hbooks/pathphys/misc_topics/ros.gif. electrons. gained. lost. Red. uction and . ox. idation reactions – . redox. . reactions. o. xygen atoms. lost. gained. A. re . these reactions . examples of oxidation or reduction?. 1. . C. . April . 2017. Forward Looking Statements. Statements in this presentation that are not descriptions of historical facts are forward-looking statements within the meaning of the . “. safe harbor. ”. Analgesics and Opioids. Analgesics are drugs that relieve pain without causing loss of consciousness.. Opioids are the . most effective pain relievers available.. Terminology. Opioid. . A general term defined as any drug, natural or synthetic, that . Organic matter generated with photosynthesis. Organic matter decomposes (. remineralized. ) during respiration. Photosynthesis. Reaction that converts CO. 2. plus nutrients (N, P, other micronutrients) to organic matter and oxygen. [2,1-. c. ][1,2,4]triazine core and their evaluation in H2O2-induced oxidative stress . . 2 - Synthetic strategies / Pharmacomodulations. Neurodegenerative disorders including Alzheimer's disease, Parkinson's disease, Huntington's disease and epilepsy are among the most serious health problems. 1675 University Blvd, WEBB 416 & 418. Lab phone:(205) 996-2661. Director: Douglas Moellering, PhD. Research Associates: . Kelley Smith-Johnston, BS: . johnk@uab.edu. Melissa J. Sammy, PhD: . mjsammy@uab.edu. Arbind Kumar R, Elna Paul and Aishwarya TV. Adverse Drug reaction is defined as the unintended response to a drug which occurs at doses normally used in man for the prophylaxis, diagnosis or therapy of disease or for the modifications of physiological functions. Tramadol is a codeine analog which is commonly used as an analgesic. Two cases of Tramadol induced vomiting are presented. A middle aged two female patients were admitted to the hospital in which one patient was diagnosed with cervical radiculopathy and lumbar disc disease and the other with acute . Reactions. 17.2 Galvanic . Cells. 17.3 Standard . Reduction Potentials. 17.4. . Concentration Cells and Nernst Equation. 17.5. . Batteries and Fuel Cells. 17.6. . Corrosion and Corrosion Prevention. 4. Redox Reactions. Oxidation-Reduction (Redox) Reactions. Redox reactions involve an electron transfer.. These reaction occur between metals and nonmetals.. Ionic reactions are redox reactions.. The name.