PPT-Models for the evolution of gene-duplicates: Applications of Phase-Type distributions.

Tristan Stark 1 David Liberles 1 Małgorzata OReilly 23 and  Barbara Holland 2 1 Temple University Philadelphia 2 University of Tasmania Australia 3 ARC Centre of Excellence for Mathematical and Statistical Frontiers ACEMS. To elucidate the structural characteristics of newly arisen gene duplicates at infancy and their subsequent evolutionary properties we analyzed gene pairs with 10 divergence at synonymous sites within the genome of Caenorhabditis elegans Structural Naama. Kraus. Slides are based on Introduction to Information Retrieval Book . by Manning, . Raghavan. and . Schütze. . Some slides are courtesy of . Kira. . Radinsky. Why duplicate detection?. Ben Spoerlein. Resident Assistant. Ball State University. Muncie, IN. Charles Darwin. (February 12. th. , 1809 – April 19. th. , 1882). Credited with providing the first convincing evidence for the theory of evolution in his immortal work, . Gamma = 1 . no alignment – true homologous positions. with muscle alignment. log. 10. (x). LBA. phyml. no-alignment. A. C. D. B. still resolved by ml . Types of Mutation-Substitution. Replacement of one nucleotide by another. G. g. Distributions. What is . G. g. ?. How are . G. g. ’s. measured?. What does the standard model predict?. Simulating . G. g. distributions.. Constraining the . Oslo method. .. Testing the Porter-Thomas distribution. I want Ms. Muirhead to know…. Blog: I will be using Ms. Martel’s blog. DNA slides are posted. . What features or characteristics does your animal have that makes it well suited for its environment/life style?. John Hancock Financial Services. What Is An Actuary?. “Actuaries are highly sought-after professionals who develop and communicate solutions for complex financial issues.”. What Do Actuaries Do?. DARWIN’S UNDERSTANDING VS. PRESENT DAY. How are inheritable traits passed?. How do variations appear?. Today’s understanding of genes, DNA, variation, and mutations is central to our understanding of how evolution works . Mechanisms of concerted evolution. Unequal cross-over. Gene conversion: non-reciprocal transfer of information between homologous sequences; the main mechanism invoked to explain concerted evolution. Stevan. J. Arnold. Oregon State University. Outline. Synthesis in evolutionary biology then and now. Simpson (1944) & the ongoing synthesis in evolutionary quantitative genetics. Two examples of the ongoing synthesis (Estes & Arnold 2007, . Answer in writing: . what is DNA? Where is yours? . A . very long macromolecules that contains your genetic material. It’s found in the nucleus of each one of your cells.. A segment of DNA which codes for a protein, which determines a trait.. J Gynecol Oncol Vol. 19, No. 4:251-255, 2008Hong-Bum Cho, et al.252Table 1. Sequences of consensus oligonucleotides used to amplifica-tion on and geneNameSequence (5' to 3')TargetReferencesGP5+GP6+G 338 1f let movement of genes. The tension between actual movement and successful is at the heart of many misunderstandings of the term 'gene stare of populations) and obtain an estimate of N(the produ Origins of Life on Earth. 4.7-4.8 Billion Year History. Evidence from chemical analysis and measurements of radioactive elements in primitive rocks and fossils. . Life developed over two main phases:.