Borodovsky a short intro Position open Scientist Pathway Informatics June 2009 THE POSITION The successful candidate will join the Computational Science amp Bioinformatics team ID: 300337
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Slide1
---- Mark
Borodovsky
a short intro
Position open:
Scientist - Pathway Informatics (June 2009)
THE POSITION
The successful candidate will join the Computational Science & Bioinformatics team
and will play a major role in the processing and
analysis of large scale data sets
from
various post genomic technologies
and their applications in biomarker discovery.
He/she will also have responsibility for
establishing and maintaining analysis
pipelines geared toward the identification of disease signature genes and pathways
from experimental system response profiles.
He/she will have the opportunity to apply and when necessary
develop methods
for systems wide analysis of gene expression patterns, their transcription factor
and epigenetic control, and the role of small RNAs in regulating gene/protein products
.
Specifically,
you will:
Establish innovative computational analysis for identification of deregulated pathways
in various disease states
Provide analysis of large scale array based data (genomics,
transcriptomics
,
proteomics
) to support the Computational Disease Biology team
THE PERSON
You have
PhD in bioinformatics
or related field
You have academic or industrial experience in bioinformatics with focus on
integrated analysis of biological systems
(gene/protein expression data,
array CGH,
ChiP
-chip)
Good programming skills in Perl, C/C++,or Java
,
you have also solid expertise in R/
Bioconductor
, or
Matlab
You have previous
experience in Gene Regulatory Network reconstruction
and pathway analysis Slide2
This International Research Training Group (IRTG) is formed by groups from
Humboldt University Berlin, Free University Berlin, Boston University,
Kyoto University and the University of Tokyo.
It focuses on the education of doctoral students
in the
emerging field of genomics and systems biology of
biomolecular
networks.
The processes to be studied carry out fundamental processes within living cells,
such as metabolic
interconversions
, cell division, cell differentiation and apoptosis.
The basic research performed in this program is highly relevant for future
medical applications, in particular with respect to cancer and other diseases
resulting from a dysfunction of signaling pathways and gene-regulatory networks.
The IRTG provides the doctoral students with a wide range of interdisciplinary
and topical research projects in four areas:
(A) Dynamics and topology of metabolic networks,
(B) Regulation of gene expression,
(C) Intra- and intercellular signal transduction, and
(D) Structure and function of protein families.Slide3
Candidates/jobs ratio
May & June 2009,
source: naturejobs.org
BINF
252
jobs
SystemsBio
21 jobsSlide4
Question #
1
Bioinformatics community has grown up earlier than the Systems Biology one;
PhD
in Bioinformatics programs has already been in place at many universities.
Now
Systems Biology may become a
new name
for a PhD major.
Should a System Biology PhD program be separate from a Bioinformatics PhD
program
?
or
Should
a PhD in Bioinformatics extend its name to PhD in Bioinformatics and
Systems
Biology (Comp Bio)?
Question #2
Will addition of
wet lab
courses to Computational Biology graduate training
lead
to loosing the Comp Bio identity?