PPT-Fluorescent Probes for Cancer Detection

Zach Dean Background Why did I choose a mathbased field Liked math classesbuildingdesigning things engineering Career Goals Professor Or Industry with a Large Company 2 nd Year Biomedical Engineering PhD Student. Each year more people die of lung cancer than of colon breast and prostate canc ers combined Most lung cancers could be prevented because they are related to smoking or secondhand smoke or less often to exposure to radon or other environmental facto Soundarya Vaithianathan. Graduate Student. Department of Medicinal Chemistry,. School of Pharmacy, VCU.. email: vaithianaths@mymail.vcu.edu. 1. February 12. th. , 2010.. WHAT ARE BIOMOLECULES ?. Biomolecules. Fluorescence Technology. Josh Leung. James Weis. February 18th, 2010. Bio 1220, Gary Wessel. Fluorescence: How does it work?. Fluorescence vs Phosphorescence. -Time delay – microsecond vs min. Photon absorbed → photon released. Zach Dean. Background. Why did I choose a math-based field?. Liked math classes/building/designing things (engineering). Career Goals:. Professor. Or Industry with a Large Company. 2. nd. Year Biomedical Engineering Ph.D. Student. Fact 1:. 40. % of women have dense . breasts. . RESULT: . Current 2D mammography makes it difficult . to detect . cancers in dense breast tissue because both appear white in the image.. Source: http. Cancer Screening & Detection. What is cancer screening?. What should I ask my doctor about cancer screening?. What are the benefits of cancer screening?. Why is early detection important?. Today. support@biogenex.com XISH VBC-321. Animal Biotechnology. A . probe. is a nucleic acid which has been . labeled. i.e., chemically modified in some way which allows it and hence anything it hybridizes to, to be detected.. There are three major types of probe: . Topics:. HCR FISH: Use HCR to Amplify Output. mRNA Imaging in Cells. Ratiometric. bimolecular beacons (RBMBs). Multiply labeled tetravalent RNA imaging probes (MTRIPs). Nanoflares. 1. 2. 3. Choi, H. M. T., Beck, V. A. & Pierce, N. A. Next-generation in situ hybridization chain reaction: higher gain, lower cost, greater durability. ACS Nano 8, 4284–4294 (2014).. Chapter 12 In Situ Hybridization for Rapid Microbiology and Cytogenetic Analysis Brett Williams, Henrik Stender, and James M. Coull From: Methods in Molecular Biology, vol. 208: Peptide Nucleic Acid Two types of non-radioactive labeling are performed- direct or indirect. Direct: Probes that are directly conjugated to a dye or an enzyme, which . generates the detection signal. Often such system involve incorporation of modified nucleotide containing a chemical group which can fluoresce when exposed to light of a certain wavelength. . Specificity and Universal Cancer Detection using Plasma. James G. Herman, M.D.. Jeff Wang, Ph.D.. The UPMC Hillman Cancer Center. The University of Pittsburgh. The Johns Hopkins University. Highly Prevalent Tumor Specific Methylation Defined for Lung CA. December 15-16, 2021 . Johns Hopkins. MGH. MGH. Washington U. UCLA. Yale. Earlier Detection of Cancer Using Non-Plasma Based Liquid Biopsies. Nick Papadopoulos and Chetan Bettegowda. Johns Hopkins School of Medicine. March 7, 2018. Walter Park, MD, MS. On behalf of PCDC Investigators. Pancreatic Cancer Detection Consortium (PCDC). Pancreatic Cancer Detection Consortium. Recalcitrant Cancer Research Act of 2012: Scientific frameworks for cancers with 5-year OS...