PPT-Addison’s, Cushing’s & Acromegaly

Tom Collins Objectives Definitions Aetiology Presentation Investigations Complications Management Prognosis Clinical scenario Addisons Disease Definition Autoimmune destruction of the adrenal gland resulting in failure of adrenal steroid hormone production. Planetary Atmospheres. The layer of gas surrounding. the Earth and other Worlds. Lecture . 13. The Planets. © 2005 Pearson Education Inc., publishing as Addison-Wesley. Planetary Atmospheres. The layer of gas surrounding. The . Seasons. Phases . of the Moon. Eclipses. Constellations. The . “Rotating Sky. ”. Lecture 3. The Planets. Prof. Geoff Marcy. . © 2005 Pearson Education Inc., publishing as Addison-Wesley. Practical Endocrinology. Wendy Blount, DVM. The Pituitary Gland. Two parts. Adenohypophysis – anterior lobe. Pars distalis. Pars intermedia. Pars infundibularis. Neurohypophysis - posterior lobe. Growth Hormone (GH) = Somatotropin. Sayed. Abdel Fattah . Eid. Lecturer of Internal Medicine. Delta University. Acromegaly . . Introduction. - Acromegaly is an insidious disorder caused by a pituitary GH-secreting adenoma resulting in high circulating levels of GH and IGF-I. . Acromegaly. Very rare. Prevalence in the order of 1 in 200,000. Usually diagnosed between age 40 and 60. No difference in gender susceptibility. Insidious onset. Pathogenesis. Most commonly caused by pituitary adenoma. National Endocrine and Metabolic Diseases Information Service US Department Human Services NATIONAL INSTITUTES hormone cortisol Sometimes called adults aged 20 to 50 People who are obese What are the What is Cushings diseaseWhat is Cushings diseaseCushings disease is a condition caused by an increased production ofthe stress hormone cortisol by the adrenal glands Increased cortisolproduction may b ResourcesEducationCounseling Service of Addison County Intensive School Support Programprovides intensive services for individuals with Autism Spectrum Disorders age 2 22Vermont Adult LearningStern Ce Mahtab. . Niroomand. . M. .D.. Assistant Professor of Endocrinology. 2014. Tehran. Out line. Introduction and epidemiology. Etiology and differential diagnosis. Clinical features. Survival . Diagnostic modality. • Today . the pituitary gland is recognized for its . essential role . in body homeostasis, and for this reason it often is referred . to as . the “. master gland. .”. • The pituitary . is a very small gland, weighing between 0.4 and 1 g . Cushing's syndrome is caused by excessive activation of glucocorticoid receptors. . By far the most common cause is iatrogenic, due to prolonged administration of synthetic glucocorticoids such as prednisolone. . Past, Present and Future. Consultant Endocrinologist, . The Christie Hospital NHS FT. Honorary Senior Lecturer, . University of Manchester . SfE. BES 2022- Conflict Of Interest . AlHawari. , MD, FACE, ECNU. Consultant Endocrinologist. Assistant Professor of . Medicine. Leena. Al-. Nsour. (MD student). D. epartment of Internal Medicine. School of Medicine. University of Jordan. Sheila Khawaja. 1. , Muriël Marks. 1. , Mark Gurnell. 2. , Maria Fleseriu. 3. . 1. World Alliance of Pituitary Organizations, Zeeland, Netherlands; . 2. Wellcome-MRC Institute of Metabolic Science, University of Cambridge & Addenbrooke’s Hospital, Cambridge, UK; .