PPT-Barbiturates

Dr S Parthasarathy MD DA DNB MD Acu Dip Diab DCA Dip Software statistics PhD physiology IDRA Synthesis Barbituric acid is not hypnotic substitution of 2 and 5 . Barbiturate General Structure and Numbering Barbiturates contain a balance of hydrophilic 246pyrimidinetrione ring structure and lipophilic 55substituents functionality The overall hydrophilic polar or lipophilic nonpolar character of the barbiturat Sedative hypnotics depress or slow down the bodys functions These drugs are commonly referred to as tranquilizers sleeping pills or sedatives They were originally developed to treat medical conditions such as epileptic seizures as well as to treat a Sedative-Hypnotics. Chapter 6. Why are CNS depressants problematic?. Usually prescribed under physician direction. Second most frequently abused prescription drug and sometimes contributes to death due to accidental overdoses. Sedative-Hypnotic Drugs. Sedative-Hypnotic Drugs. Drugs that depress CNS function. Primarily used to treat anxiety and insomnia. Antianxiety agents or anxiolytics. Distinction between antianxiety effects and hypnotic effects is often a matter of dosage. By: Jessica Sachsenmaier. What is a depressant?. A depressant is a substance that slows down the normal function of the central nervous system. . Drugs that fall under the depressant category are barbiturates, benzodiazepines, and alcohol. . Anxiolytics. :. Benzodiazepines & others. Tracy A. Womble, . Ph.D. Florida A&M University . College of Pharmacy and Pharmaceutical Sciences. SEDATIVE-HYPNOTICS . History of Sedatives. Alcohol, the oldest known sedative. Dr. Sana Fatima. BARBITURATES. Derivatives of . Barbituric. Acid. . Barbituric. acid itself has no sedative effect. . No more used as sedative hypnotics but are applied as general anesthetics due to. Why do we sleep?. Sleep is a basic requirement for normal brain function. . Lack of sleep .  . Mental fatigue, . poor decision-making, . shortened attention span, . higher anxiety, . impaired memory, . . So set the (strained) relations right between your brothers and fear . allah. . . (. 49:10). A Verse From Holy Quran. 2. TO SPEAK A KIND WORD . IS CHARITY. . {. For which, One deserves a reward from Allah (JS)}. Blanton. Hypnotic Agents. Hypnotic Agents Produce. :. . -. state of drowsiness. -promote onset and maintenance . of sleep. . Patient can be awakened readily.. -Treatment of Insomnia. Antianxiety. Dr.Kumari. . Anjana. Assistant Professor. Deptt. . of Veterinary Pharmacology & Toxicology. Bihar Veterinary College, Bihar Animal Sciences University, Patna. INTRAVENOUS ANESTHETICS. Barbiturates . PING AND t.C. JENKINS ULTIMATE EFFECT of hypoxia is oxygen deficiency at the mitochondrial level. The brain is particularly sensitive to hypoxia and this, taken with the inability of brain tissue to . Anjana. Assistant Professor. Deptt. . of Veterinary Pharmacology & Toxicology. Bihar Veterinary College, Bihar Animal Sciences University, Patna. Overview of the chapter . Introduction (. Sedatives, Hypnotics. The barbiturate are 5,5’-disubstituted . barbituric. acid. * . The . structure of 5,5-disubstituted . barbituric. acids reveals their acidic character.. .  . General procedure for barbiturate .