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Continuous Nerve Block Infusions:  Use in Children and Ado Continuous Nerve Block Infusions:  Use in Children and Ado

Continuous Nerve Block Infusions:  Use in Children and Ado - PowerPoint Presentation

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Continuous Nerve Block Infusions:  Use in Children and Ado - PPT Presentation

Kelley Windsor PCNSBC Lane Faughnan RN Objectives Describe the experience of managing continuous peripheral nerve block catheters CPNBs at our pediatric hem onc institution Describe the nursing implications in managing pediatric patients with CPNBs as inpatients and outpatients ID: 317842

pain block catheter nerve block pain nerve catheter days dressing catheters site patient day 2005 peripheral cpnb silver 2011

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Slide1

Continuous Nerve Block Infusions:  Use in Children and Adolescents in Both Inpatient or Outpatient Settings

Kelley Windsor, PCNS-BC

Lane Faughnan, RNSlide2

Objectives

Describe the experience of managing continuous peripheral nerve block catheters (CPNBs) at our pediatric hem/

onc

institution

Describe the nursing implications in managing pediatric patients with CPNBs as inpatients and outpatients

Identify strategies to prevent and manage complications of CPNB

Review case studies

Time for questions and discussionSlide3

Our experience, 2005-2011Slide4

Background information

St. Jude Children’s Research Hospital treats children and young adults with life-threatening diseases of childhood, mostly cancer

60 inpatient bed facility, large outpatient service

Started using CPNB catheters in 2005

Prior to 2005, epidurals were our standard regional pain management

Started with one anesthesiologist, then expanded to all anesthesiologists placing nerve block cathetersSlide5

Our experience 2005-2011: Incidence and indications

248 Catheters

155 patients

About 50:50

male:female

Surgical

Indications (91%)

Limb-sparing surgery

AmputationProsthesis revisionTumor resection Closed manipulationOther orthopedic surgeries

Non-surgical

indications (9%)

Pathological fractures

Tumor-related pain

End of life regional painSlide6

Our experience 2005-2011: Patient diagnoses

%

of 248 catheters

placed;

patients may have had simultaneous or recurrent cathetersSlide7

Incidence and duration of CPNB by Indication: Surgical vs Non-surgical

Block indication

Surgical

Non-surgical

Patients

141

14

Catheters (%)

226 (91.1)

22 (8.9%)

Catheter-days

1337

439

Infections

(% catheters)4 (1.8)2 (9.1)Duration mean (days)5.920Duration median (days)513.5Duration range (days)1-295-81Slide8

50.8%

Number and duration of

CPNBs by year

*One block of 81 days was reported in 2008 (end of life pain management) and affects the average duration data for 2008. Excluding this block, the average is 7.8 days duration.

Average duration

Median duration

C

atheters over 7 days

Number of CathetersSlide9

Our experience 2005-2011: Block sitesSlide10

Our experience 2005-2011: Location of care

CPNB totals for 2005 - 2011:

248 catheters

1776 catheter days

68.6% of these days were

inpatient

days

31.4

% of these days were outpatient days

123 catheters had outpatient days (average time

outpt

: 4.6 days)

5 patients (5 catheters) were placed as outpatients with

no inpatient staySlide11

Neuroanatomy

:

l

ower extremity

Editors:

Chelly

, Jacques

E. Title

: Peripheral Nerve Blocks: A Color Atlas, 3rd

Edition Copyright

©2009 Lippincott Williams & WilkinsSlide12

Brachial Plexus after forequarter amputationSlide13

Our experience 2005-2011: block infusions

Medications:

bupivacaine

or

ropivacaine

; tried

clonidine

, but no anecdotal support for useInfusion rates: vary, based on size of patient and location of blockSlide14

Our experience 2005-2011: nerve block infusions

Analgesic efficacy:

efficacy of NBI therapy in children and adults has been well documented in the literature

Dressing changes

: started with

tegaderm

, then silver impregnated dressings, back to

tegaderm

, back to silver impregnated dressingsRemoval of catheter: done inpatient or in pain clinic ; duration of catheter depends on type of surgery or indicationsSlide15

Fall 2009

Winter

2009

Spring

2010

Summer 2010

Fall

2010

Winter 2010

Spring 2011

Summer 2011

Fall 2011

Winter 2011

Spring 2012

Silver dressingIncluded in CPNB kitNo silver dressing included Silver dressing

Included in CPNB kit

No silver dressing included

Silver dressing

recommended but packaged separately

Silver Dressing Use with CPNB at St. Jude: Infections

3 cases each w and w/o the silver dressing

July Sept 2010

May (2) July Sept 2011

May 2011: change in dressing change practice/providerSlide16

Nursing implications: inpatient and outpatient managementSlide17

Known Complications

Infection

Exit site

Tunnel track

Device malfunctions

Broken catheter

Dislodged / accidental removal

Pump disconnection

Pump malfunctionInfusion leakAnalgesia complications

Incomplete block or inadequate pain control

Numbness

Potential interference with patient care

Not compatible with

MRI

Location of catheters related to activities of daily living / physical therapySlide18

Risk Factors for Infection

Results from

adult studies:

ICU stay

Block duration >48h

Male

Lack of antibiotic prophylaxis

Axillary or femoral location

Frequent dressing changes

Source:

Capdevila

, X.,

Bringuier

, S., &

Borgeat, A. (2009). Infectious risk of continuous peripheral nerve blocks. Anesthesiology, 110(1), 182-188.Slide19

Standard of Care: Inpatient

Assessment and Documentation:

Every fours hours (pain score, block exit site, dressing clean and dry, connections secure, motor strength)

Change infusion bag and tubing q96h

Patient Safety:

Two independent double checks for initiation of infusion, bag changes, and dosage changes

Quality improvement process for every day that infusion is running

Patient and Family Education:

Identify appropriate patients for keeping NBI for outpatientHow long will they need the nerve block?Is there a caregiver to manage pump?Preparing written handouts (Do You Know)Slide20

Standard of Care: Outpatients

Assessment and Documentation:

NBI site and dressing assessed with each outpatient clinic visit

Change dressing every 7 days or if soiled or wet

Pump checks done with visits to Pain Clinic

Patient Safety:

Two independent double checks for initiation of infusion, bag changes, and dosage changes

Quality improvement process for every day that infusion is running

All bag changes are done by RNs at the hospitalTeaching done prior to patient leaving the hospital (going into hospital housing) Oncall MD as support for any problems with block

Patient and Family Education

Do You Know…Nerve Block Infusions

Do You Know…CADD Solis Pump

Pain DiarySlide21
Slide22

Available in SpanishSlide23

strategies

to prevent and manage complications of

CPNB:

Patient careSlide24

Preventing Complications

Insertion Techniques

Sterile technique

Tunneling catheters

Dressing

Type of dressing (silver impregnated

vs

not)

Frequency of dressing change (every 7 days, or when dirty or loose)Site AssessmentSlide25

Managing Complications: Disconnected catheter

Assess patient: means a trip to medicine room

A

ssess catheter – broken or disconnected?

If broken:

We would typically discontinue the catheter

Anesthesiologist may repair it if indicated (end of life) or schedule patient for new catheter

If disconnected:

Parents are taught to protect integrity of catheter tip with red capContaminated bags are discontinued and new bag hooked upSlide26

Managing Complications: Leaking catheter

Assess patient; assess catheter – leaking from pump, tubing, or exit site?

Kinked or occluded? Trouble shoot to find problem.

Leaking at exit site? Reduce infusion rate.

Leaking from tubing or pump? Replace bag and/or pumpSlide27

Managing Complications: Incomplete pain control

Assessment: phone call or clinic visit

Pain assessment and review PRN pain medication usage and effectiveness

With or without cold test

Intervention

May bolus NBI with local anesthetic to test effectiveness

If bolus works, may increase rate or concentration of anesthetic

If not, may discontinue blockSlide28

strategies

to prevent and manage complications of

CPNB:

Quality ImprovementSlide29

Improvement Goals: QI

Reduce infection at site

Ensure antibiotic coverage, especially in the non-surgical patients

Improvement of nursing documentation

To meet standard of care inpatient and outpatientSlide30

Improvement Goals: Nursing Education

Pain Pointers

Epidural/Nerve Block Calculator

Improve use of current pt/family education materialsSlide31

Improvement Goals: Nursing Education

Epidural/Nerve Block Calculator (online)Slide32

Improvement Goals: New Devices and Techniques

Devices:

CADD Solis: new pump with drug library

Techniques:

Continue sterile technique, including gown

USG and nerve stimulator

Tunnel all catheters

Dressing:

Use silver impregnated dressingRemove catheter within one week, unless end of lifeSlide33

Improvement Goals: Responding to QI

Each adverse event should be carefully reviewed as early as possible to identify contributing factors

“Minor” or “expected” events should also be gathered and reviewed for increasing trends that signal a lapse in policy or a new problem

Changes in staffing

New device or supplierSlide34

Number of blocks and

number of infections, by yearSlide35

Summary of 6 infections

Primary diagnosis

Age (years)

Pain source

Block

site

ICU days/ catheter duration (days)

Antibiotic coverage (not counting

Septra

)

Signs of infection (day of diagnosis)

Temperature at time of CPNB removal

ANC range during block

Osteo

-sarcoma (OS)18.3Primary limb-sparing surgery

Sciatic

10

Day 0:

Before

and after catheter insertion

Days

1 –

8

: daily

(ceftriaxone, cefuroxime, gentamicin,

vancomycin

)

 

 

4100-14,600

Femoral

3/10

Erythema around catheter site

(Day 10)

Unknown

OS

18

Primary limb-sparing surgery

Femoral

8

C

efuroxime +

Vanc

on procedure

day, and one day post

 

8/17

femoral

site

cellulitis;

required PO antibiotics; 8/19, cellulitis worse, required admission/IV antibiotics; febrile

36.8 (

8/1)

600-4500

Sciatic

8

 

OS

18

Pathological fracture

Femoral

0/13

Day 0:

after catheter insertion

Induration and coagulase-negative staphylococci on catheter tip (

Day 13)

37.5°C

8700-37,200

OS

10

Pathological fracture

Femoral

10

Day

0:

Clinda

on day 0, Days 1-14: daily (

vanc

,

clinda

,

mero

,

etc

)

 

redness, fever, pain at site

(started 5/13)

39.3

100

– 38,500

Sciatic

14

site painful (started 5/18),

report of fever

37.9

OS

17

Primary limb-sparing surgery

Femoral

2/11

Cef

/

Vanc

day 0 and 1 only

 

Unknown

4400-8600

Sciatic

2/11

 

OS

21

Limb sparing revision

Femoral

6

 

Cef

/

Vanc

day 0

only

cellulitis

of entry site

site

at

routine visit

;

d/c

cath

; culture of tip which grew

coag

neg

staph

37.9

6900-9500Slide36

Special circumstances

CPNB risk/benefit profile is unique for every patient

Pain control at end of life is priority over relative risks such as neutropenia, thrombocytopenia, local wound, or other contraindications

We have allowed CPNB to remain in site for prolonged periods under some end-of-life circumstances:

Catheter is controlling pain effectively (better than PCA or PO)

Catheter is functioning properly

Pt

/family willing, remain available for catheter maintenance (home health or outpatient visits)Slide37

Risk/Benefit of Regional Analgesia for End of Life Pain Management

Case

Device type

ANC

(x10

3

/L)

Platelet count (x10

6

/L)

Other contraindications

1

E

5300

283

T12 fracture, spinal metastases, fever

2

NB

8300

362

 

3.1

NB

6300

39

Spinal metastases

3.2

E

nd

94

3.3

E

4600

26

4

E

2100

84

 

5

E

4100

123

 

6

NB

1300

89

Large wound in targeted area

7.1

E

6300

477

 

7.2

E

22300

488

8

E

5800

20

Fever

9

E

5400

241

 

10.1

E

4500

76 (trx)

 

10.2

E

4800

106 (trx)

E=epidural;

NB=nerve block

; ANC=absolute neutrophil count;

nd

=not done;

trx

=value after transfusion(s)

 

Anghelescu et al, 2010Slide38

Case studiesSlide39

Discussion / QuestionsSlide40

Selected References

Anghelescu, D. L., Faughnan, L. G., Baker, J. N., Yang, J., & Kane, J. R. (2010).

Use of epidural and peripheral nerve blocks at the end of life in children and young adults with cancer: the collaboration between a pain service and a palliative care service.

Paediatr

Anaesth

, 20

(12), 1070-1077.Anghelescu, D. L., Harris, B. L., Faughnan, L. G., Oakes, L. L., Windsor, K. B., Wright, B. B., et al. (2012). Risk of catheter-associated infection in young hematology/oncology patients receiving long-term peripheral nerve blocks. Paediatr

Anaesth

.

Burgoyne, L., Pereiras, L.,

Bertani

, L., Kaddoum, R., Neel, M., Faughnan, L., et al. (2012). Long-term use of nerve block catheters in paediatric patients with cancer related pathologic fractures. Anaesth Intensive Care, 40(4), 710-713.Capdevila, X., Bringuier, S., & Borgeat, A. (2009). Infectious risk of continuous peripheral nerve blocks. Anesthesiology, 110(1), 182-188.Capdevila, X., Pirat, P., Bringuier, S., Gaertner, E., Singelyn, F., Bernard, N., et al. (2005). Continuous peripheral nerve blocks in hospital wards after orthopedic surgery: a multicenter prospective analysis of the quality of postoperative analgesia and complications in 1,416 patients. Anesthesiology, 103(5), 1035-1045.Dadure, C., Bringuier, S., Raux, O., Rochette, A., Troncin, R., Canaud, N., et al. (2009). Continuous peripheral nerve blocks for postoperative analgesia in children: feasibility and side effects in a cohort study of 339 catheters. Can J Anaesth, 56(11), 843-850.Dadure, C., & Capdevila, X. (2012). Peripheral catheter techniques. Paediatr Anaesth, 22(1), 93-101.Dadure, C., Motais, F., Ricard, C., Raux, O., Troncin, R., & Capdevila, X. (2005). Continuous peripheral nerve blocks at home for treatment of recurrent complex regional pain syndrome I in children. Anesthesiology, 102(2), 387-391.Ganesh, A., Rose, J. B., Wells, L., Ganley, T., Gurnaney, H., Maxwell, L. G., et al. (2007). Continuous peripheral nerve blockade for inpatient and outpatient postoperative analgesia in children. Anesth Analg, 105(5), 1234-1242, table of contents.Ludot, H., Berger, J., Pichenot, V., Belouadah, M., Madi, K., & Malinovsky, J. M. (2008). Continuous peripheral nerve block for postoperative pain control at home: a prospective feasibility study in children. Reg Anesth Pain Med, 33(1), 52-56.