3337 European Review for Medical and Pharmacological Sciences2017 21 33373338 Bullae formation in tramadol intoxication an unusual presentation Figure 1 Bullae formation on right pinna in case of ID: 938481
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3337 Dear Editor,A 27-year-old man went to the Emergency Department with lethargy and confusion. His history before. On initial evaluation, his pulse was 110 beats/min and oxygen saturation was 94% in room air. asymptomatic. On the next day, he stated he had a persistent neck pain, which was unresponsive to regular dose of tramadol. He remembered that he ingested more than the usual number of tramadol ear (Figure 1). No other bullae were found on other parts of the body. Bullous skin lesions (known other etiologies in which the presumed mechanism is proposed inadequacy of circulation in pressure . However, bulla formation in non-comatose intoxicated case is rare and may be European Review for Medical and Pharmacological Sciences2017; 21: 3337-3338 Bullae formation in tramadol intoxication: a
n unusual presentation Figure 1. Bullae formation on right pinna in case of tramadol intoxication. 3338 Conflict of interestThe authors declare no con�icts of interest. OCHA J, PEI T, VEN F, PDAL F, B . Coma Blisters. Case Rep Dermatol 2009; 27: 66-70. ND K . Bullae in comatose and non-comatose patients. Acta Derm Venereol 2003; 83: 236-237. UIHEAD T. A case of coma blisters in a non-pressure dependent distribution. J Am Acad Dermatol 2011; 64: AB95. ENG M, AGOS M, IEPMAN MR, T K Phenobarbital-induced bullous lesions in a non-comatose patient. Psychiatry (Edgmont) 2006; 3: 65-69. ING W, ANDILANDSEA Coma blisters. Clin Toxicol (Phila) 2007; 45: 808-809.Department of Forensic Medicine and Toxicology, Bu Ali Hospital, Qazvin University of Medical Sciences, Qazvin, Iran S.M. Mirakbari