PPT-Pain, Inflammation, NSAIDs and Analgesics

BY DR KAUKAB AZIM 1 Learning Outcomes By the end of the lecture the student should be able to Define and discuss the pathobiology of pain pathways Explain the molecular mechanism of action common to all . Manpreet . & . Olivia . Outline. Pain Receptors . WHO Pain Ladder. Pain . Treatment . . -> Types of Analgesics. . - NSAIDs. . - Opioids. . What are the . 2 main . types of pain?. Neuropathic pain. Drugs for Treating . P. ain. Perception of Pain. Emotion. S. ocial . and environmental . context. S. ocio-cultural background. Beliefs. Attitudes. P. ersonal expectations. Physical perturbations. P. sychological . Osteoarthritis (OA) is the most common joint disease, affecting nearly 50% of those over 65 years of age and almost all individuals over age 75.. OA affects primarily the weight-bearing joints of the axial and peripheral skeleton, causing pain, limitation of motion, deformity, progressive disability, and decreased quality of life.. Evaluating the Risks and Benefits. Most Frequently Used OTC Analgesics. Reasons Why These Drugs Are Widely Used. What Limits the Use of OTC Drugs?. Adverse Effects of OTC Analgesics. Efficacy of Aspirin in Headache. # . PHL 322, Lab. . 3# . Introduction. - Pain:. an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage. - Analgesics :. Program Overview. The Burden of Pain in RA and OA. Evolution of NSAID Use. COX Selectivity:. COX-1 and COX-2. CV Risks With NSAIDs. Other Risks With NSAIDs. The Impact of Pain in RA and OA. Pain Relief Is a Priority for People With RA and OA. NURS 1950. Pharmacology. Nancy Pares, RN, MSN. Metro Community College. 1. Pain is:. Pain tolerance is:. 2. Obj. 1 Define pain and Pain tolerance. Objective 2: Identify the factors which affect the individual’s response to pain. What is an analgesic?. How do you feel pain?. What does “physical dependence” mean? . What does ‘tolerance’ mean in this context?. Analgesics – reduce pain. Mild analgesics. . Mild analgesics, such as . P. ain. Perception of Pain. Emotion. S. ocial . and environmental . context. S. ocio-cultural background. Beliefs. Attitudes. P. ersonal expectations. Physical perturbations. P. sychological . recognition . . . Kumari. . Anjana. Assistant Professor. Deptt. . of Veterinary Pharmacology & Toxicology. Bihar Veterinary College, Bihar Animal Sciences University, Patna. Opioid analgesics. Are the drugs that significantly relieve pain by acting in central nervous system or on peripheral mechanisms without affecting consciousness.. A. nti-. I. nflammatory . D. rug. S. Professor Sue . Smith. National Heart and Lung Institute. sue.smith@imperial.ac.uk. Major Clinical Uses. Relief of mild-to-moderate pain (Analgesic). Toothache, headache, backache . 1-3. .. NSAIDs have anti-inflammatory, analgesic, and anti-pyretic proprieties, mediated by blockade of the COX enzymes, and subsequent inhibition of prostaglandin synthesis. 4,5. .. Several over-the-counter NSAIDs have demonstrated efficacy in treating headache and migraine. Phoebe Cinco. 11/26/18. Objectives. After attending this case presentation, participants will be able to:. Explain the pathophysiology of chronic muscular back pain. Describe the Epidemiology of chronic muscular back pain. What you need to know. Age Child, adult, older people . Symptoms Pain, swelling, site and duration . History . Injury . Medical conditions . Medication. Sprains. A sprain injury involves the overstretching of ligaments and/or the joint capsule, sometimes with tearing..