PPT-Stereochemistry and Chirality

Penny Commons Brendan Abrahams February STAV Workshop Copyright issues We have replaced the images with their urls Please just click on the url and copy the image into the PowerPoint Any free images have been left in place. Enantiomers stereoisomers whose molecules are nonsuperposable mirror images 2 Diastereomers stereoisomers whose molecules are not mirror images of each other Example cis and trans double bond isomers Example cis and trans cycloalkane isomers Two t Conformational isomers can be shown using Newman Projections or Sawhorses Newman Projections The circle in the Newman projection represents the carboncarbon bond viewed one carbon in front of the other Bonds attached to the front carbon are shown by longer than a monomeric subunits of 468 residues each - total mol. wt. of 600,000 1. Chapter 5. Stereochemistry. Chiral Molecules. About The Authors. . These Powerpoint Lecture Slides were created and prepared by Professor William Tam and his wife Dr. Phillis Chang. . . Professor William Tam received his B.Sc. at the University of Hong Kong in 1990 and his Ph.D. at the University of Toronto (Canada) in 1995. He was an NSERC postdoctoral fellow at the Imperial College (UK) and at Harvard University (USA). He joined the Department of Chemistry at the University of Guelph (Ontario, Canada) in 1998 and is currently a Full Professor and Associate Chair in the department. Professor Tam has received several awards in research and teaching, and according to . Configuration. While conformational isomers are . interconvertable. through rotations about single bonds, . configurational. isomers require bond-breaking and reforming for . interconversion. .. Stereoisomers. CanTherm. 27. th. Sept 2013. Shamel Merchant. What is . CanTherm. CanTherm. Thermodynamic Properties. Kinetic rate coefficients. Gaussian. What is . CanTherm. CanTherm. is written in python and can be used for the following calculations. Optical isomers rotate plane polarised light in opposite directions: . one rotates light clockwise and the other anticlockwise. . A mixture containing equal amounts of each isomer is known as a . racemic mixture. 1.1 Astrobiology There are a lot of astronomical objects that human beings have been observing so far. Findings of new type of celestial bodies have been encouraging us to make a step toward new idea C. Young and Richard J. Hooley. Department of Chemistry. University of California, Riverside. Chirality and the Origins of Life:. A Case Study in Organic Chemistry. 1. Carsten and Charles were having a philosophical discussion on the origins of life in the universe. Carsten had been reading some literature on the topic. This stated that the fact that amino acids are . Isomerism. Isomerism. is the phenomenon whereby certain compounds, with the same molecular formula, exist in different forms owing to their different organizations of atoms. The concept of isomerism illustrates the fundamental importance of molecular structure and shape in organic chemistry.. What is the relationship between R,S and . d,l. aka (±)?. There isn’t any!. Interaction with plane polarized light. Nomenclature. All . Isomers . (same molecular formula). Identical. . Enantiomers. that optical isomerism is a result of chirality in molecules with a . single chiral . centre. understand . that optical isomerism results from chiral centre(s) in . a molecule with . asymmetric carbon atom(s) and that optical isomers are object . 3.3: Chirality and stereoisomers. What is chiral?. Chiral objects . don’t have an internal plane of symmetry, aka a . mirror plane . of . symmetry.. When superimposed, chiral objects don’t overlap perfectly.. members. >10 . million. . organic. . compounds. !. How to . identify. . them. ?. . Molecular. formula. C. 4. H. 10. Extended. s. tructural. formula. Partially. . condensed. . structural. formula.